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      Reduced Population Burden of Road Transport–related Major Trauma After Introduction of an Inclusive Trauma System

      research-article
      , PhD, MBiostat, MAppSc * , , , , MB, MPH, MD, FFPHMI, FFPH * , , , MBBS, FACEM, MRACMA , , MBBS, FRACS, FRCS, FACS § , , PhD , , MBBS, MD, FACEM * ,
      Annals of Surgery
      Lippincott Williams & Wilkins
      burden of injury, costs, disability-adjusted life years, outcomes, trauma

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          Abstract

          This population-based study found that since the introduction of an inclusive, regionalized trauma system in Victoria, Australia, the burden of road transport–related serious injury has decreased. Hospitalized major trauma cases increased, but disability burden per case declined. Increased survival did not result in an overall increase in nonfatal injury burden.

          Abstract

          Objective:

          To describe the burden of road transport–related serious injury in Victoria, Australia, over a 10-year period, after the introduction of an integrated trauma system.

          Background:

          Road traffic injury is a leading cause of death and disability worldwide. Efforts to improve care of the injured are important for reducing burden, but the impact of trauma care systems on burden and cost of road traffic injury has not been evaluated.

          Methods:

          All road transport–related deaths and major trauma (injury severity score >12) cases were extracted from population-based coroner and trauma registry data sets for July 2001 to June 2011. Modeling was used to assess changes in population incidence rates and odds of in-hospital mortality. Disability-adjusted life years, combining years of life lost and years lived with disability, were calculated. Cost of health loss was calculated from estimates of the value of a disability-adjusted life year.

          Results:

          Incidence of road transport–related deaths decreased (incidence rate ratio 0.95, 95% confidence interval: 0.94–0.96), whereas the incidence of hospitalized major trauma increased (incidence rate ratio 1.03, 95% confidence interval: 1.02–1.04). Years of life lost decreased by 43%, and years lived with disability increased by 32%, with an overall 28% reduction in disability-adjusted life years over the decade. There was a cost saving per case of A$633,446 in 2010–2011 compared with the 2001–2002 financial year.

          Conclusions:

          Since introduction of the trauma system in Victoria, Australia, the burden of road transport–related serious injury has decreased. Hospitalized major trauma cases increased, whereas disability burden per case declined. Increased survival does not necessarily result in an overall increase in nonfatal injury burden.

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          Most cited references21

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          A national evaluation of the effect of trauma-center care on mortality.

          Hospitals have difficulty justifying the expense of maintaining trauma centers without strong evidence of their effectiveness. To address this gap, we examined differences in mortality between level 1 trauma centers and hospitals without a trauma center (non-trauma centers). Mortality outcomes were compared among patients treated in 18 hospitals with a level 1 trauma center and 51 hospitals non-trauma centers located in 14 states. Patients 18 to 84 years old with a moderate-to-severe injury were eligible. Complete data were obtained for 1104 patients who died in the hospital and 4087 patients who were discharged alive. We used propensity-score weighting to adjust for observable differences between patients treated at trauma centers and those treated at non-trauma centers. After adjustment for differences in the case mix, the in-hospital mortality rate was significantly lower at trauma centers than at non-trauma centers (7.6 percent vs. 9.5 percent; relative risk, 0.80; 95 percent confidence interval, 0.66 to 0.98), as was the one-year mortality rate (10.4 percent vs. 13.8 percent; relative risk, 0.75; 95 percent confidence interval, 0.60 to 0.95). The effects of treatment at a trauma center varied according to the severity of injury, with evidence to suggest that differences in mortality rates were primarily confined to patients with more severe injuries. Our findings show that the risk of death is significantly lower when care is provided in a trauma center than in a non-trauma center and argue for continued efforts at regionalization. Copyright 2006 Massachusetts Medical Society.
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              Impracticability of informed consent in the Registry of the Canadian Stroke Network.

              Government legislators and research ethics boards in some jurisdictions require all patients to give written informed consent before enrollment in clinical registries. However, the effect of such a requirement on the use of clinical registries and the extent to which registry data can be generalized remain uncertain. We examined the effectiveness of a comprehensive attempt to obtain informed consent between June 2001 and December 2002 on the overall participation rate and the characteristics of participating patients in the Registry of the Canadian Stroke Network, a prospective registry based at 20 major stroke centers across Canada. The overall participation rate (i.e., the consent rate among all potential participants) was 39.3 percent of 4285 eligible patients during phase 1 of the project (June 2001 through February 2002) and 50.6 percent of 2823 eligible patients during phase 2 (June 2002 through December 2002), despite the presence of neurologic research nurse coordinators at each site. Many patients died or left the hospital before they could be approached for consent. Major selection biases were found; the in-hospital mortality rate was much lower among patients who were enrolled (6.9 percent) than among those who were not enrolled (21.7 percent) (relative risk of in-hospital death, 3.13; 95 percent confidence interval, 2.65 to 3.70; P<0.001). We estimate that approximately 500,000 dollars (Canadian dollars) was spent on consent-related issues during the first two years of the registry. Obtaining written informed consent for participation in a stroke registry led to important selection biases, such that registry patients were not representative of the typical patient with stroke at each center. These findings highlight the need for legislation on privacy and policies permitting waivers of informed consent for minimal-risk observational research. Copyright 2004 Massachusetts Medical Society
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                Author and article information

                Journal
                Ann Surg
                Ann. Surg
                ANSU
                Annals of Surgery
                Lippincott Williams & Wilkins
                0003-4932
                1528-1140
                March 2015
                10 February 2015
                : 261
                : 3
                : 565-572
                Affiliations
                [* ]Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
                []College of Medicine, Swansea University, Swansea, Wales, UK
                []Trauma Centre, The Alfred Hospital, Melbourne, Victoria, Australia
                [§ ]Trauma Service, Royal Melbourne Hospital, Melbourne, Victoria, Australia
                []Centre for Health Economics, Monash University, Melbourne, Victoria, Australia; and
                []Emergency and Trauma Centre, The Alfred Hospital, Melbourne, Victoria, Australia.
                Author notes
                [*]Reprints: Belinda Gabbe, PhD, MBiostat, MAppSc, Department of Epidemiology and Preventive Medicine, The Alfred Centre, Monash University, 99 Commercial Rd, Melbourne, Victoria, Australia 3004. E-mail: belinda.gabbe@ 123456monash.edu .
                Article
                ansu26103p565
                10.1097/SLA.0000000000000522
                4337622
                24424142
                b8adf6a8-b9b4-452a-936c-41349824ef0e
                © 2014 Wolters Kluwer Health, Inc. All rights reserved.

                This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

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                burden of injury,costs,disability-adjusted life years,outcomes,trauma

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