31
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Novel Biopolymer-Based Composite Wound Healing Wafers Containing Astragalus sarcocolla Gum

      1 ,
      British Journal of Pharmacy
      University of Huddersfield Press

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The aim of this research was the formulation development, optimisation and characterisation of wafers produced from various combinations of carrageenan  and tragacanth gum as potential carriers for wound healing extracts. Gels composed of one of the following three polymers: carrageenan (CAR), tragacanth gum (TG) and hydroxypropyl methylcellulose (HPMC) were prepared and freeze dried to obtain single polymer blank wafers. The blank wafers were examined for required lyophilisation behaviour and physical elegance of the resulting product. Based on these results, HPMC was eliminated and a combination of CAR:TG at seven different polymer ratios was chosen for further research. These CAR:TG wafers were characterised using scanning electron microscope (SEM), X-ray diffraction(XRD), texture analysis (hardness and mucoadhesion), Fourier transform infraredspectroscopy (FTIR), swelling tests and fluid handling properties. The formulations with the optimal properties were selected for loading with the extract and the drug-loaded wafers were subsequently further characterised as above.

          Author and article information

          Journal
          British Journal of Pharmacy
          University of Huddersfield Press
          2058-8356
          April 21 2022
          November 4 2022
          : 7
          : 2
          Affiliations
          [1 ]Faculty of Engineering and Science, Greenwich university
          Article
          10.5920/bjpharm.1154
          b8b5c1e7-7e31-4751-860b-8fb40ecde856
          © 2022

          https://creativecommons.org/licenses/by/4.0

          History

          Comments

          Comment on this article