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      An extremely rare case of testicular malign neoplasm; alveolar subtype of rhabdomyosarcoma with long term follow-up

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          Clinical characteristics and overall survival in genitourinary sarcomas treated with curative intent: a multicenter study.

          Adult soft tissue sarcomas in general, and those arising from the urological organs in particular, are a group of rare tumours with a generally poor prognosis, only a few studies are available. We report our experience with this type of tumours in a multicenter study carried out in a single region of Central Italy (Tuscany). Pre-treatment and follow-up data were obtained from 22 adult patients, all residing in Tuscany, treated consecutively between 1984 and 2002 for primary or locally recurrent genito-urinary sarcomas in 8 urology departments in the area. All cases were classified according to the French Federation of Cancer Center System Grading Scheme for Adult Sarcomas (FFCC) and Broders System. The crude survival probability was estimated by using the Kaplan-Meier method and differences between patient sub-groups were assessed by the log rank test. The study series included 18 males and 4 females. The mean age at diagnosis was 61+/-21.5 years (range: 15.3-89.1). The most common site was paratesticular (n=9, 40.9%), followed by kidney (n=8, 36.4%), prostate (n=3, 13.6%) and penis and bladder (1 case each, 4.6%). 15 cases (68.2%) were classified as FFCC III, and 16 (72.7%) as Broders IV. The most common histological type was leiomyosarcoma (8 cases, 36.7%), followed by liposarcoma (6, 27.3%), rhabdomyosarcoma (3, 13.6%) and other histological types (5, 22.7%). At the last follow-up (mean: 3.66+/-3.25 years; range 0.15-10.0), 11 of the 22 patients (50%) were still alive. The overall survival rate at 1, 3 and 5 years was 85.9%, 62.0% and 48.8%, respectively. There were no significant differences in survival according to sex, age or histological type. When we compared paratesticular vs. kidney and prostate cancer cases, a significant difference in survival emerged (p=0.02). According to size and grade of the tumour we also found a significant difference in survival (p=0.0006 and p=0.01, respectively). In our representative series, 3 tumor parameters (site, size and grade) appeared to represent the most important prognostic factors in adult genitourinary sarcomas.
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            Paratesticular desmoplastic small round cell tumor with metastasis: A report of two cases

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              Adult paratesticular tumors

               B Khoubehi,  V Mishra,  M Ali (2002)
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                Author and article information

                Journal
                JHS
                Journal of Health Sciences
                University of Sarajevo Faculty of Health Studies (Bosnia )
                2232-7576
                1986-8049
                2014
                : 4
                : 2
                : 134-135
                Affiliations
                [1 ]Department of Urology, Baskent University Alanya Research Hospital, Alanya, Antalya, Turkey
                [2 ]Department of Urology, Harran University School of Medicine, Sanliurfa, Turkey
                Author notes
                [* ]Corresponding author: Yigit Akin, M.D. Assistant Professor of Urology, Department of Urology, Harran University School of Medicine, 63100, Sanliurfa, Turkey. Tel: +90-506-533 49 99, Fax: +90-414-318 30 05. E-mail: yigitakin@ 123456yahoo.com
                Article
                JHS-4-134
                Copyright: © Tumay Ipekci, et al

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Product
                Self URI (journal page): http://www.jhsci.ba/OJS/index.php/jhsci
                Categories
                LETTER TO EDITOR

                Nursing, General medicine, Medicine, Molecular medicine, Life sciences

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