278
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Genetic patterns in Neotropical Magnolias (Magnoliaceae) using de novo developed microsatellite markers

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references45

          • Record: found
          • Abstract: found
          • Article: not found

          Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.

          Linkage disequilibrium--the nonrandom association of alleles at different loci--is a sensitive indicator of the population genetic forces that structure a genome. Because of the explosive growth of methods for assessing genetic variation at a fine scale, evolutionary biologists and human geneticists are increasingly exploiting linkage disequilibrium in order to understand past evolutionary and demographic events, to map genes that are associated with quantitative characters and inherited diseases, and to understand the joint evolution of linked sets of genes. This article introduces linkage disequilibrium, reviews the population genetic processes that affect it and describes some of its uses. At present, linkage disequilibrium is used much more extensively in the study of humans than in non-humans, but that is changing as technological advances make extensive genomic studies feasible in other species.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Accuracy of estimated phylogenetic trees from molecular data

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Current trends in microsatellite genotyping.

              Microsatellites have been popular molecular markers ever since their advent in the late eighties. Despite growing competition from new genotyping and sequencing techniques, the use of these versatile and cost-effective markers continues to increase, boosted by successive technical advances. First, methods for multiplexing PCR have considerably improved over the last years, thereby decreasing genotyping costs and increasing throughput. Second, next-generation sequencing technologies allow the identification of large numbers of microsatellite loci at reduced cost in non-model species. As a consequence, more stringent selection of loci is possible, thereby further enhancing multiplex quality and efficiency. However, current practices are lagging behind. By surveying recently published population genetic studies relying on simple sequence repeats, we show that more than half of the studies lack appropriate quality controls and do not make use of multiplex PCR. To make the most of the latest technical developments, we outline the need for a well-established strategy including standardized high-throughput bench protocols and specific bioinformatic tools, from primer design to allele calling. © 2011 Blackwell Publishing Ltd.
                Bookmark

                Author and article information

                Journal
                Heredity
                Heredity
                Springer Nature America, Inc
                0018-067X
                1365-2540
                October 27 2018
                Article
                10.1038/s41437-018-0151-5
                b9067e5b-5a1d-4be1-b39d-e0e4f659cd25
                © 2018

                http://creativecommons.org/licenses/by/4.0

                History

                Comments

                Comment on this article