5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Adequate tumour cellularity is essential for accurate PD ‐L1 immunohistochemistry assessment on cytology cell‐block specimens

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          PD-L1 immunohistochemistry (IHC) is an essential predictive biomarker for patients with non-small cell lung cancer (NSCLC), required to inform treatment decisions regarding anti-PD-1 immune checkpoint inhibitor therapy. This study aims to investigate the concordance between PD-L1 IHC assessed on NSCLC cytology and histology specimens and to determine the impactce of tumour cellularity.

          Related collections

          Most cited references2

          • Record: found
          • Abstract: not found
          • Book: not found

          IASLC atlas of PD-L1 immunohistochemistry testing in lung cancer

            Bookmark
            • Record: found
            • Abstract: not found
            • Book: not found

            WHO Classification of Tumours of the Lung, Pleura, Thymus, and Heart

              Bookmark

              Author and article information

              Contributors
              Journal
              Cytopathology
              Cytopathology
              Wiley
              0956-5507
              1365-2303
              January 21 2020
              March 2020
              January 11 2020
              March 2020
              : 31
              : 2
              : 90-95
              Affiliations
              [1 ]Department of Pathology at Peter MacCallum Cancer Centre Melbourne VIC Australia
              [2 ]Department of Pathology at St Vincent's Hospital Melbourne VIC Australia
              [3 ]Department of Pathology at Royal Melbourne Hospital Melbourne VIC Australia
              [4 ]Department of Respiratory & Sleep MedicineRoyal Melbourne Hospital Melbourne VIC Australia
              [5 ]Department of Medicine (RMH)University of Melbourne Melbourne VIC Australia
              [6 ]Sydney Medical SchoolUniversity of Sydney Sydney NSW Australia
              [7 ]Tissue Pathology and Diagnostic OncologyRoyal Prince Alfred Hospital Sydney NSW Australia
              [8 ]School of MedicineWestern Sydney University Sydney NSW Australia
              [9 ]Department of Medical Oncology at the University of Melbourne Melbourne VIC Australia
              Article
              10.1111/cyt.12795
              31808243
              b9174572-ba3f-47cc-9ff1-d826124e0c70
              © 2020

              http://onlinelibrary.wiley.com/termsAndConditions#vor

              http://doi.wiley.com/10.1002/tdm_license_1.1

              History

              Comments

              Comment on this article