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      Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review.

      1 ,

      The Journal of infectious diseases

      University of Chicago Press

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          Abstract

          Information on age- and sex-specific prevalence of herpes simplex virus (HSV) types 2 and 1 infections is essential to optimize genital herpes control strategies, which increase in importance because accumulating data indicate that HSV-2 infection may increase acquisition and transmission of human immunodeficiency virus. This review summarizes data from peer-reviewed publications of type-specific HSV seroepidemiologic surveys. HSV-2 prevalence is, in general, highest in Africa and the Americas, lower in western and southern Europe than in northern Europe and North America, and lowest in Asia. HSV-2 and -1 prevalence, overall and by age, varies markedly by country, region within country, and population subgroup. Age-specific HSV-2 prevalence is usually higher in women than men and in populations with higher risk sexual behavior. HSV-2 prevalence has increased in the United States but national data from other countries are unavailable. HSV-1 infection is acquired during childhood and adolescence and is markedly more widespread than HSV-2 infection. Further studies are needed in many geographic areas.

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          Author and article information

          Journal
          J Infect Dis
          The Journal of infectious diseases
          University of Chicago Press
          0022-1899
          0022-1899
          Oct 15 2002
          : 186 Suppl 1
          Affiliations
          [1 ] International Agency for Research on Cancer (IARC), Unit of Field and Intervention Studies, 69372 Lyon, France. smith@iarc.fr
          Article
          JID020147
          10.1086/343739
          12353183
          b91b3906-7e9d-4a73-9126-d2154bd47094

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