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Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.
M Givskov , R de Nys , M Manefield , L Gram , R Maximilien , L Eberl , S Molin , P D Steinberg , S Kjelleberg
1996
1996
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Abstract
Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication
among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites
which have structural similarities to AHL molecules. We report here that these metabolites
inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction
between higher organisms and their surface-associated bacteria may be mediated by
interference with bacterial regulatory systems.
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Author and article information
Journal
Journal of bacteriology
American Society for Microbiology
0021-9193
1996
1996
: 178
: 22
: 6618-6622
Article
10.1128/JB.178.22.6618-6622.1996
178549
8932319
b9294331-ddf8-48ee-aa2d-3b1e2e032240
©
1996
Product
Self URI (article page):
https://JB.asm.org/content/178/22/6618