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      Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.

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          Abstract

          Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these metabolites inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.

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          Author and article information

          Journal
          Journal of bacteriology
          American Society for Microbiology
          0021-9193
          1996
          1996
          : 178
          : 22
          : 6618-6622
          Article
          10.1128/JB.178.22.6618-6622.1996
          178549
          8932319
          b9294331-ddf8-48ee-aa2d-3b1e2e032240
          © 1996
          Product
          Self URI (article page): https://JB.asm.org/content/178/22/6618

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