- Record: found
- Abstract: not found
- Article: not found
Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.
M Givskov ,
R de Nys ,
M Manefield ,
L Gram ,
R Maximilien ,
L Eberl ,
S Molin ,
P D Steinberg ,
S Kjelleberg
1996
1996
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication
among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites
which have structural similarities to AHL molecules. We report here that these metabolites
inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction
between higher organisms and their surface-associated bacteria may be mediated by
interference with bacterial regulatory systems.