Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression.

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Abstract

To investigate the role of microRNA-193b-3p (miR-193b) in the vascular pathophysiology of systemic sclerosis (SSc).

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Author and article information

Journal

Journal ID (iso-abbrev): Ann. Rheum. Dis.

Title: Annals of the rheumatic diseases

Publisher: BMJ

ISSN (Electronic): 1468-2060

ISSN (Print): 0003-4967

Publication date (Electronic): Jan 2016

Volume: 75

Issue: 1

Affiliations

[1 ] Division of Rheumatology, Center of Experimental Rheumatology, University Hospital and Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

[2 ] Division of Rheumatology, Center of Experimental Rheumatology, University Hospital and Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland.

[3 ] Division of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland.

[4 ] Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

[5 ] Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.

Article

Publisher Item ID: annrheumdis-2014-205326

DOI: 10.1136/annrheumdis-2014-205326

PubMed ID: 25384965

SO-VID: b93fcf5d-738a-4eb4-b11a-5c806460006d

History

Keywords: Arterial Hypertension,Autoimmune Diseases,Systemic Sclerosis

Data availability:

Keywords: Arterial Hypertension, Autoimmune Diseases, Systemic Sclerosis

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