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      Effects of metformin on weight loss: potential mechanisms.

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          Abstract

          Despite the known glucose-lowering effects of metformin, more recent clinical interest lies in its potential as a weight loss drug. Herein, we discuss the potential mechanisms by which metformin decreases appetite and opposes unfavorable fat storage in peripheral tissues.

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          Author and article information

          Journal
          Curr Opin Endocrinol Diabetes Obes
          Current opinion in endocrinology, diabetes, and obesity
          1752-2978
          1752-296X
          Oct 2014
          : 21
          : 5
          Affiliations
          [1 ] aDepartment of Pathobiology, Lerner Research Institute, Cleveland Clinic bDepartment of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, Ohio, USA.
          Article
          10.1097/MED.0000000000000095
          25105996
          b94ab2a0-fe1a-4b4f-a78f-e93505bec80e
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