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      Recent advances in the production of value added chemicals and lipids utilizing biodiesel industry generated crude glycerol as a substrate - Metabolic aspects, challenges and possibilities: An overview.

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          Abstract

          One of the major ecological concerns associated with biodiesel production is the generation of waste/crude glycerol during the trans-esterification process. Purification of this crude glycerol is not economically viable. In this context, the development of an efficient and economically viable strategy would be biotransformation reactions converting the biodiesel derived crude glycerol into value added chemicals. Hence the process ensures the sustainability and waste management in biodiesel industry, paving a path to integrated biorefineries. This review addresses a waste to wealth approach for utilization of crude glycerol in the production of value added chemicals, current trends, challenges, future perspectives, metabolic approaches and the genetic tools developed for the improved synthesis over wild type microorganisms were described.

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          Author and article information

          Journal
          Bioresour. Technol.
          Bioresource technology
          Elsevier BV
          1873-2976
          0960-8524
          Sep 2017
          : 239
          Affiliations
          [1 ] Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, Kerala, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-NIIST, Thiruvananthapuram 695 019, Kerala, India.
          [2 ] Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, Kerala, India.
          [3 ] Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, Kerala, India; Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram 695 014, Kerala, India.
          [4 ] Department of Chemical, Environmental and Materials Engineering, University of Jaén, Campus Las Lagunillas, 23071 Jaén, Spain.
          [5 ] Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte S. Angelo, via Cintia 4, 80126 Naples, Italy.
          [6 ] Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, Kerala, India; Center of Innovative and Applied Bioprocessing, Sector 81, Mohali 160 071, Punjab, India.
          [7 ] Microbial Processes and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695 019, Kerala, India. Electronic address: binodkannur@gmail.com.
          Article
          S0960-8524(17)30710-1
          10.1016/j.biortech.2017.05.056
          28550990
          b9ad8c91-3163-453f-bac8-8ea9c898ee03
          History

          Crude glycerol,Metabolic engineering,Process strategies,Value added products

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