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      Extensive genetic diversity in Blastocystis hominis

      Molecular and Biochemical Parasitology
      Elsevier BV

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          Abstract

          Blastocystis homonis is a common human parasite of uncertain role in human disease. Approximately equal numbers of reports implicate it and exonerate it as a pathogen. Genetic diversity in B. hominis was investigated using riboprinting to study sequence variation in the small subunit ribosomal RNA genes of 30 randomly selected isolates. Extensive sequence variation was discovered in B. hominis ribosomal RNA genes and this species consists of at least seven morphologically identical but genetically quite distinct organisms. If only a subset of the B. hominis variants have the potential to cause disease in humans this might explain the disparate findings reported. Future clinical studies must take the heterogeneity of B. hominis into account.

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          Author and article information

          Journal
          Molecular and Biochemical Parasitology
          Molecular and Biochemical Parasitology
          Elsevier BV
          01666851
          July 1997
          July 1997
          : 87
          : 1
          : 79-83
          Article
          10.1016/S0166-6851(97)00046-7
          9233675
          b9eb0376-1496-47f7-91e0-27e07a5281d4
          © 1997

          https://www.elsevier.com/tdm/userlicense/1.0/

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