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Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study.
Adrian F Daly
1 ,
Maria A Tichomirowa ,
Patrick Petrossians ,
Elina Heliövaara ,
Marie-Lise Jaffrain-Rea ,
Anne Barlier ,
Luciana A Naves ,
Tapani Ebeling ,
Auli Karhu ,
Antti Raappana ,
Laure Cazabat ,
Ernesto De Menis ,
Carmen Fajardo Montañana ,
Gerald Raverot ,
Robert J Weil ,
Timo Sane ,
Dominique Maiter ,
Sebastian Neggers ,
Maria Yaneva ,
Antoine Tabarin ,
Elisa Verrua ,
Eija Eloranta ,
Arnaud Murat ,
Outi Vierimaa ,
Pasi I Salmela ,
Philippe Emy ,
Rodrigo A Toledo ,
Maria Isabel Sabaté ,
Chiara Villa ,
Marc Popelier ,
Roberto Salvatori ,
Juliet Jennings ,
Angel Ferrandez Longás ,
José Ignacio Labarta Aizpún ,
Marianthi Georgitsi ,
Ralf Paschke ,
Cristina Ronchi ,
Matti Valimaki ,
Carola Saloranta ,
Wouter De Herder ,
Renato Cozzi ,
Mirtha Guitelman ,
Flavia Magri ,
Maria Stefania Lagonigro ,
Georges Halaby ,
Vinciane Corman ,
Marie-Thérèse Hagelstein ,
Jean-François Vanbellinghen ,
Gustavo Barcelos Barra ,
Anne-Paule Gimenez-Roqueplo ,
Fergus J Cameron ,
Françoise Borson-Chazot ,
Ian Holdaway ,
Sergio P A Toledo ,
Günter K Stalla ,
Anna Spada ,
Sabina Zacharieva ,
Jerome Bertherat ,
Thierry Brue ,
Vincent Bours ,
Philippe Chanson ,
Lauri A Aaltonen ,
Albert Beckers
Nov 2010
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Abstract
AIP mutations (AIPmut) give rise to a pituitary adenoma predisposition that occurs in familial isolated pituitary adenomas and less often in sporadic cases. The clinical and therapeutic features of AIPmut-associated pituitary adenomas have not been studied comprehensively.