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      Clinical characteristics and PTPN22 1858C/T variant analysis in Jordanian Arab vitiligo patients.

      Molecular Diagnosis & Therapy
      Springer Nature America, Inc

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          Abstract

          Vitiligo is an autoimmune polygenic disorder, characterized by loss of pigmentation due to melanocyte destruction. Multiple genes and environmental triggers are thought to play a role in inducing vitiligo. These genes and environmental factors differ across different populations. In this study, we investigated vitiligo patients in Jordan for patient characteristics and analyzed the association of the 1858C/T (rs2476601, R620W) variant of the PTPN22 gene with vitiligo in our patients.

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          Journal
          20560680
          10.2165/11537180-000000000-00000

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