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      Health Risk Assessment of Heavy Metals from Smoked Corbicula fluminea Collected on Roadside Vendors at Kelantan, Malaysia

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          Abstract

          Corbicula fluminea serves as traditional food to the local people in Kelantan, Malaysia. Concerns regarding river contamination, smoking method, and associated adverse effects on public health had been increasing. Hence, this study aims to measure the level of heavy metals (Cd, Cu, Mn, Pb, and Zn) and assess human health risk in C. fluminea consumption at Kelantan. Heavy-metal analysis was done using flame atomic absorption spectrophotometry, while human health risk was assessed using provisional tolerable weekly intake (PTWI), target hazard quotient (THQ), and hazard index (HI). The estimated weekly intake (EWI) for all metals was found within PTWI, while THQ for Cd, Cu, Mn, Pb, and Zn was 0.12, 0.06, 0.04, 0.41, and 0.03, respectively. The HI was calculated at 0.61 which is less than 1, considered as the safe consumption level. Therefore, C. fluminea consumption in this study was found safe from the health risk of noncarcinogenic effect over a lifetime.

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          Pb Neurotoxicity: Neuropsychological Effects of Lead Toxicity

          Neurotoxicity is a term used to describe neurophysiological changes caused by exposure to toxic agents. Such exposure can result in neurocognitive symptoms and/or psychiatric disturbances. Common toxic agents include heavy metals, drugs, organophosphates, bacterial, and animal neurotoxins. Among heavy metal exposures, lead exposure is one of the most common exposures that can lead to significant neuropsychological and functional decline in humans. In this review, neurotoxic lead exposure's pathophysiology, etiology, and epidemiology are explored. In addition, commonly associated neuropsychological difficulties in intelligence, memory, executive functioning, attention, processing speed, language, visuospatial skills, motor skills, and affect/mood are explored.
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            Transfer of heavy metals through terrestrial food webs: a review.

            Heavy metals are released into the environment by both anthropogenic and natural sources. Highly reactive and often toxic at low concentrations, they may enter soils and groundwater, bioaccumulate in food webs, and adversely affect biota. Heavy metals also may remain in the environment for years, posing long-term risks to life well after point sources of heavy metal pollution have been removed. In this review, we compile studies of the community-level effects of heavy metal pollution, including heavy metal transfer from soils to plants, microbes, invertebrates, and to both small and large mammals (including humans). Many factors contribute to heavy metal accumulation in animals including behavior, physiology, and diet. Biotic effects of heavy metals are often quite different for essential and non-essential heavy metals, and vary depending on the specific metal involved. They also differ for adapted organisms, including metallophyte plants and heavy metal-tolerant insects, which occur in naturally high-metal habitats (such as serpentine soils) and have adaptations that allow them to tolerate exposure to relatively high concentrations of some heavy metals. Some metallophyte plants are hyperaccumulators of certain heavy metals and new technologies using them to clean metal-contaminated soil (phytoextraction) may offer economically attractive solutions to some metal pollution challenges. These new technologies provide incentive to catalog and protect the unique biodiversity of habitats that have naturally high levels of heavy metals.
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              Using the Asian clam as an indicator of microplastic pollution in freshwater ecosystems.

              Bioindicators play an important role in understanding pollution levels, bioavailability and the ecological risks of contaminants. Several bioindicators have been suggested for understanding microplastic in the marine environment. A bioindicator for microplastics in the freshwater environment does not exist. In our previous studies, we found a high frequency of microplastic pollution in the Asian clam (Corbicula fluminea) in Taihu Lake, China. In the present study, we conducted a large-scale survey of microplastic pollution in Asian clams, water and sediment from 21 sites in the Middle-Lower Yangtze River Basin from August to October of 2016. The Asian clam was available in all sites, which included diverse freshwater systems such as lakes, rivers and estuaries. Microplastics were found at concentrations ranging from 0.3-4.9 items/g (or 0.4-5.0 items/individual) in clams, 0.5-3.1 items/L in water and 15-160 items/kg in sediment. Microfibers were the most dominant types of microplastics found, accounting for 60-100% in clams across all sampling sites. The size of microplastics ranged from 0.021-4.83 mm, and microplastics in the range of 0.25-1 mm were dominant. The abundance, size distribution and color patterns of microplastics in clams more closely resembled those in sediment than in water. Because microplastic pollution in the Asian clam reflected the variability of microplastic pollution in the freshwater environments, we demonstrated the Asian clam as an bioindicator of microplastic pollution in freshwater systems, particularly for sediments.
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                Author and article information

                Contributors
                Journal
                Biomed Res Int
                Biomed Res Int
                BMRI
                BioMed Research International
                Hindawi
                2314-6133
                2314-6141
                2019
                30 September 2019
                : 2019
                : 9596810
                Affiliations
                1Department of Natural Resource and Sustainability, Universiti Malaysia Kelantan, Jeli Campus, Locked Bag No. 100, 17600 Jeli, Kelantan, Malaysia
                2Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Johor, Malaysia
                Author notes

                Academic Editor: Francesco Dondero

                Author information
                https://orcid.org/0000-0002-5451-7297
                https://orcid.org/0000-0003-2093-5113
                Article
                10.1155/2019/9596810
                6791190
                ba9bc30c-2273-422f-bf19-f2c43c167278
                Copyright © 2019 Koh Han Dee et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 11 May 2019
                : 27 August 2019
                : 6 September 2019
                Funding
                Funded by: Ministry of Higher Education, Malaysia
                Award ID: R/TRGS/A08.00/00244A/005/2016/000389
                Categories
                Research Article

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