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Overview and findings from the rush Memory and Aging Project.

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      Abstract

      The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort study of common chronic conditions of aging with an emphasis on decline in cognitive and motor function and risk of Alzheimer's disease (AD). In this manuscript, we first summarize the study design and methods. Then, we present data on: (1) the relation of motor function to cognition, disability, and death; (2) the relation of risk factors to cognitive and motor outcomes, disability and death; (3) the relation of neuropathologic indices to cognitive outcomes; (4) the relation of risk factors to neuropathologic indices; and (5) additional study findings. The findings are discussed and contextualized.

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      Author and article information

      Affiliations
      [1 ] Rush Alzheimer's Disease Center, Rush University Medical Center, 600 S. Paulina, Suite 1028, Chicago, IL 60612, USA. David_A_Bennett@Rush.edu
      Journal
      Curr Alzheimer Res
      Current Alzheimer research
      1875-5828
      1567-2050
      Jul 2012
      : 9
      : 6
      CAR-EPUB-20120402-008
      22471867
      3439198
      NIHMS386797

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