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      Kaposi’s Sarcoma in a Patient with Erythroblastopenia and Thymoma: Reactivation after Topical Corticosteroids

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          Abstract

          We report a 69-year-old female with erythroblastopenia and thymoma who developed lesions of Kaposi’s sarcoma (KS) after thymectomy, 2 months after the initiation of therapy with methylprednisolone. Control of mucocutaneous KS lesions was obtained with radiotherapy, interferon alfa-2b and withdrawal of systemic immunosuppressive therapy. Erosive oral lichen planus appeared later, and after therapy with topical corticosteroids a new lesion of KS developed that regressed after withdrawal of topical corticosteroids. The detection of HHV-8 only in lesional skin supports the hypothesis that this virus can trigger the development of KS lesions.

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          Most cited references3

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          Oral tetracycline treatment on bacterial flora in acne vulgaris

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            • Record: found
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            Telangiectatic Kaposi's sarcoma. Occurrence in a patient with thymoma and myasthenia gravis receiving long-term immunosuppressive therapy.

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              • Record: found
              • Abstract: not found
              • Article: not found

              Kaposi's sarcoma with thymoma

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                Author and article information

                Journal
                DRM
                Dermatology
                10.1159/issn.1018-8665
                Dermatology
                S. Karger AG
                1018-8665
                1421-9832
                1998
                1998
                05 October 1998
                : 197
                : 3
                : 264-267
                Affiliations
                Departments of aDermatology and bPathology, Hospital de la Sta. Creu i St. Pau, and cDepartment of Haematology, Clínica de Salud La Alianza, Barcelona, Spain, and dDepartment of Dermatology, LMU, Munich, Germany
                Article
                18010 Dermatology 1998;197:264–267
                10.1159/000018010
                9812034
                badd0928-65bc-4384-b364-bf8a31586c2b
                © 1998 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Page count
                Figures: 4, References: 32, Pages: 4
                Categories
                Case Report

                Oncology & Radiotherapy,Pathology,Surgery,Dermatology,Pharmacology & Pharmaceutical medicine
                Kaposi’s sarcoma,HHV-8,Corticosteroids,Thymoma,Female,Erythroblastopenia

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