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      Local anesthetic 'in-situ' toxicity during peripheral nerve blocks: update on mechanisms and prevention.

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          Abstract

          Peripheral nerve blocks induce undesired side-effects linked to the toxicity of local anesthetics on neuron and myocytes via different cell targets. The effects of local anesthetics on these targets are now well known and summarized in this review.

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          Author and article information

          Journal
          Curr Opin Anaesthesiol
          Current opinion in anaesthesiology
          1473-6500
          0952-7907
          Oct 2012
          : 25
          : 5
          Affiliations
          [1 ] University Bordeaux, Maladies Rares, Génétique et Métabolique, Bordeaux, France. karine.nouette-gaulain@chu-bordeaux.fr
          Article
          10.1097/ACO.0b013e328357b9e2
          22914357

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