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      Brachytherapy versus external beam radiotherapy boost for prostate cancer: Systematic review with meta-analysis of randomized trials.

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          Abstract

          Brachytherapy boost after external beam radiotherapy for intermediate and high-risk prostate cancer is presented as an attractive technique in numerous retrospective and prospective studies. Currently, three randomized controlled trials comparing brachytherapy versus external beam radiotherapy boost used non-homogenous irradiation features. Therefore, we analyzed the oncological outcomes by a systematic review with meta-analysis of the randomized controlled trials.

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          Author and article information

          Journal
          Cancer Treat. Rev.
          Cancer treatment reviews
          Elsevier BV
          1532-1967
          0305-7372
          Nov 2018
          : 70
          Affiliations
          [1 ] Department of Radiotherapy, Centre Antoine Lacassagne, University of Cote d'Azur, Nice, France.
          [2 ] Biostatistics Unit, Centre Antoine Lacassagne, University of Cote d'Azur, Nice, France.
          [3 ] Department of Radiotherapy, Centre Antoine Lacassagne, University of Cote d'Azur, Nice, France. Electronic address: jean-michel.hannoun-levi@nice.unicancer.fr.
          Article
          S0305-7372(18)30166-X
          10.1016/j.ctrv.2018.10.004
          30326422

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