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      Clinical Effect of Short Daily In-Center Hemodialysis

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          Abstract

          Background: The safety and efficacy of short daily hemodialysis has been reported in the USA and Europe, but there is no report on its efficacy in Japanese patients undergoing hemodialysis. Methods: Twenty-three outpatients (14 men and 9 women, 55.8 ± 9.6 years old and 11.1 ± 6.6 years on dialysis) undergoing hemodialysis 3 times/week participated in this study. After 4 weeks’ baseline observation under conventional hemodialysis, they were subjected to short daily in-center hemodialysis (DHD, 6 times/week) for 12 weeks and then a 4-week follow-up observation period under conventional hemodialysis. Results: The mean pre-dialysis systolic and diastolic blood pressure significantly decreased in the DHD period. Antihypertensive drugs could be discontinued or the dose was reduced in 6 of 11 patients treated with such drugs. The hematocrit level tended to increase in the DHD period, and recombinant human erythropoietin could be discontinued or reduced in 7 of 14 patients. Localized skin rash caused by the adhesive tape and lidocaine patch at the blood access was observed in only 2 patients, but no other adverse events associated with DHD were noted. Conclusion: These results indicate that DHD is safe and more useful than conventional 3 times/week hemodialysis for Japanese patients undergoing hemodialysis.

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          Hemeral (Daily) Hemodialysis

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            Rationale for Daily Hemodialysis

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              Author and article information

              Journal
              NEC
              Nephron Clin Pract
              10.1159/issn.1660-2110
              Nephron Clinical Practice
              S. Karger AG
              1660-2110
              2003
              September 2003
              17 November 2004
              : 95
              : 1
              : c23-c30
              Affiliations
              aInternal Medicine, Showa University Fujigaoka Hospital, Yokohama; bCenter of Blood Purification Therapy, Wakayama Medical University, Wakayama, and cInstitute of Medical Science, Tokai University, Isehara, Japan
              Article
              73015 Nephron Clin Pract 2003;95:c23–c30
              10.1159/000073015
              14520018
              © 2003 S. Karger AG, Basel

              Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

              Page count
              Figures: 4, Tables: 3, References: 14, Pages: 1
              Product
              Self URI (application/pdf): https://www.karger.com/Article/Pdf/73015
              Categories
              Original Paper

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