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      Clinical Effect of Short Daily In-Center Hemodialysis

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          Background: The safety and efficacy of short daily hemodialysis has been reported in the USA and Europe, but there is no report on its efficacy in Japanese patients undergoing hemodialysis. Methods: Twenty-three outpatients (14 men and 9 women, 55.8 ± 9.6 years old and 11.1 ± 6.6 years on dialysis) undergoing hemodialysis 3 times/week participated in this study. After 4 weeks’ baseline observation under conventional hemodialysis, they were subjected to short daily in-center hemodialysis (DHD, 6 times/week) for 12 weeks and then a 4-week follow-up observation period under conventional hemodialysis. Results: The mean pre-dialysis systolic and diastolic blood pressure significantly decreased in the DHD period. Antihypertensive drugs could be discontinued or the dose was reduced in 6 of 11 patients treated with such drugs. The hematocrit level tended to increase in the DHD period, and recombinant human erythropoietin could be discontinued or reduced in 7 of 14 patients. Localized skin rash caused by the adhesive tape and lidocaine patch at the blood access was observed in only 2 patients, but no other adverse events associated with DHD were noted. Conclusion: These results indicate that DHD is safe and more useful than conventional 3 times/week hemodialysis for Japanese patients undergoing hemodialysis.

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          Hemeral (Daily) Hemodialysis

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            Rationale for Daily Hemodialysis


              Author and article information

              Nephron Clin Pract
              Nephron Clinical Practice
              S. Karger AG
              September 2003
              17 November 2004
              : 95
              : 1
              : c23-c30
              aInternal Medicine, Showa University Fujigaoka Hospital, Yokohama; bCenter of Blood Purification Therapy, Wakayama Medical University, Wakayama, and cInstitute of Medical Science, Tokai University, Isehara, Japan
              73015 Nephron Clin Pract 2003;95:c23–c30
              © 2003 S. Karger AG, Basel

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              Page count
              Figures: 4, Tables: 3, References: 14, Pages: 1
              Self URI (application/pdf): https://www.karger.com/Article/Pdf/73015
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