7
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Emerging indications for extracorporeal membrane oxygenation in adults with respiratory failure.

      Annals of the American Thoracic Society
      Anoxia, therapy, Extracorporeal Circulation, methods, Extracorporeal Membrane Oxygenation, Humans, Hypercapnia, Lung Transplantation, Pulmonary Disease, Chronic Obstructive, Respiration, Artificial, Respiratory Distress Syndrome, Adult, Respiratory Insufficiency, Severity of Illness Index, Tidal Volume, Ventilator-Induced Lung Injury, prevention & control

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Recent advances in technology have spurred the increasing use of extracorporeal membrane oxygenation (ECMO) in patients with severe hypoxemic respiratory failure. However, this accounts for only a small percentage of patients with respiratory failure. We envision the application of ECMO in many other forms of respiratory failure in the coming years. Patients with less severe forms of acute respiratory distress syndrome, for instance, may benefit from enhanced lung-protective ventilation with the very low tidal volumes made possible by direct carbon dioxide removal from the blood. For those in whom hypercapnia predominates, extracorporeal support will allow for the elimination of invasive mechanical ventilation in some cases. The potential benefits of ECMO may be further enhanced by improved techniques, which facilitate active mobilization. Although ECMO for these and other expanded applications is under active investigation, it has yet to be proven beneficial in these settings in rigorous controlled trials. Ultimately, with upcoming and future technological advances, there is the promise of true destination therapy, which could lead to a major paradigm shift in the management of respiratory failure.

          Related collections

          Author and article information

          Comments

          Comment on this article