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      The effect of Aloe Vera gel on prevention of pressure ulcers in patients hospitalized in the orthopedic wards: a randomized triple-blind clinical trial

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          Abstract

          Background

          One of the most common orthopedic problems is the incidence of pressure ulcer followed by immobility. This study aimed to investigate the effect of Aloe Vera gel on the prevention of pressure ulcer in patients hospitalized in the orthopedic ward.

          Method

          This study is a randomized, triple-blind clinical trial which was done on 80 purposefully selected patients in orthopedic ward in Arak town, Iran, 2016. Patients were randomly assigned into two intervention and control groups based on blocking sampling method. In each group the routine daily cares to prevent bed sores were performed by nurses. In the intervention group in addition to routine nursing care to prevent bed sores, twice a day (hours of 9 and 21) pure Aloe Vera gel on the areas of hip, sacrum and heel were rubbed, but in the control group placebo (gel of water and starch) were used. Then sacral, hip and heel of both groups on days 3, 7 and 10 for of signs of pressure ulcers was evaluated.

          Results

          The mean age of patients in the control group was (42.34 ± 12.19) and in the intervention group Was (41.71 ± 11.50) years, respectively. In the intervention group 1 patient afflicted with sore of hip and two people with sacral pressure ulcer. In the control group 3 patients affiliated with sore of hip, 8 people with sacral pressure ulcer, and 1 person had pressure sore of heel. Analysis of the data showed that both groups had statistically significant differences in the incidence of pressure ulcers ( P = 0.047). This means that Aloe Vera gel could prevent the occurrence of pressure ulcers in the intervention group.

          Conclusion

          Due to the effect of Aloe Vera gel to prevent a rise in temperature, non-blanchable redness, swelling and pain of the skin of regions under study in hospitalized patients in the orthopedic ward, applying of it toward the prevention of pressure ulcers in patients at risk of pressure ulcer development is recommended.

          Trial registration

          This study was registered in Iranian Registry of Clinical. Trials in 07/09/2016 with the IRCT ID: IRCT2016051027825N1.

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          Most cited references58

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          An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera.

          Aloe barbadensis (Miller), Aloe vera, has a long history of use as a topical and oral therapeutic. The plant is the source of two products, gel and latex, which are obtained from its fleshy leaves. Aloe vera products contain multiple constituents with potential biological and toxicological activities, yet the active components elude definition. Ingestion of Aloe vera is associated with diarrhea, electrolyte imbalance, kidney dysfunction, and conventional drug interactions; episodes of contact dermatitis, erythema, and phototoxicity have been reported from topical applications. This review examines the botany, physical and chemical properties, and biological activities of the Aloe vera plant.
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            Therapeutic and Medicinal Uses of <i>Aloe vera</i>: A Review

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              Literature review of pain prevalence among older residents of nursing homes.

              Pain is a common symptom among older residents of nursing homes and can lead to adverse effects such as a decrease in the activities of daily living and quality of life. Existing literature on the prevalence of pain among older residents of nursing homes was reviewed. Of the studies that were reviewed here, 27 met the criteria of this study, and these were selected for further analysis. These studies were published from 1990 to 2009. There was a slight increase in the number of studies on this topic from 2004 onwards. It was clear that older residents commonly suffer from pain and other serious problems related to pain. The prevalence of pain in these studies appeared to be related to the research methods and data sources used as well as to the time frame of pain detection. Therefore, the results of such prevalence studies should be interpreted cautiously. It was also reported that higher pain intensity led to greater limitations in the activities of daily living. Insufficient use of analgesics for treating residents with pain was often reported, particularly in residents with a low cognitive status. Health professionals should be aware of the serious issues related to pain among nursing home residents and the fundamental right to have pain assessed and treated to the greatest extent possible. Copyright © 2010 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.
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                Author and article information

                Contributors
                dr_hekmat@arakmu.ac.ir , hekmatpou@yahoo.com
                Fmehrabi1392@gmail.com , Fmehrabi1370@yahoo.com
                K.rahzani@yahoo.com
                atefeh.aminian@yahoo.com
                Journal
                BMC Complement Altern Med
                BMC Complement Altern Med
                BMC Complementary and Alternative Medicine
                BioMed Central (London )
                1472-6882
                29 September 2018
                29 September 2018
                2018
                : 18
                : 264
                Affiliations
                [1 ]ISNI 0000 0001 1218 604X, GRID grid.468130.8, Academic member of Nursing and Midwifery Faculty, , Arak University of Medical Sciences, ; Basij Sq., Payambar-e-Azam Educational Complex, Arak, Iran
                [2 ]ISNI 0000 0001 1218 604X, GRID grid.468130.8, Nursing and Midwifery Faculty, , Arak University of Medical Sciences, ; Arak, Iran
                [3 ]ISNI 0000 0001 1218 604X, GRID grid.468130.8, Clinical Pharmacology, , Academic member of Arak University of Medical Sciences, ; Arak, Iran
                Author information
                http://orcid.org/0000-0002-2350-9155
                Article
                2326
                10.1186/s12906-018-2326-2
                6162886
                30268162
                bbc3a967-acac-4252-8f12-98372c390414
                © The Author(s). 2018

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 21 February 2018
                : 13 September 2018
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2018

                Complementary & Alternative medicine
                aloe vera,prevention,pressure ulcer,orthopedic ward
                Complementary & Alternative medicine
                aloe vera, prevention, pressure ulcer, orthopedic ward

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