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      Processing of prosodic cues of uncertainty in autistic and non-autistic adults: a study based on articulatory speech synthesis

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          Abstract

          Introduction

          We investigated the prosodic perception of uncertainty cues in adults with Autism Spectrum Disorder (ASD) compared to neurotypical adults (NTC).

          Method

          We used articulatory synthetic speech to express uncertainty in a human-machine scenario by varying the three acoustic cues pause, intonation, and hesitation. Twenty-eight adults with ASD and 28 NTC adults rated each answer for uncertainty, naturalness, and comprehensibility.

          Results

          Both groups reliably perceived different levels of uncertainty. Stimuli were rated as less uncertain by the ASD group, but not significantly. Only when we pooled the recipients’ ratings for all three cues, did we find a significant group difference. In terms of reaction time, we observed longer reaction times in the ASD group compared to the neurotypical comparison group for the uncertainty level hesitation & strong intonation, but the differences were not significant after Bonferroni correction. Furthermore, our results showed a significant group difference between the correlation of uncertainty and naturalness, i.e. the correlation in the ASD group is significantly lower than in the NTC group. Obtained effect size estimates can inform sample size calculations in future studies for the reliable identification of group differences.

          Discussion

          In future work, we would like to further investigate the interaction of all three cues and uncertainty perception. It would be interesting to further vary the duration of the pause and also to use different types of fillers. From a developmental perspective, uncertainty perception should also be investigated in children and adolescents with ASD.

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          Most cited references115

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          Autism spectrum disorder

          Autism spectrum disorder is a term used to describe a constellation of early-appearing social communication deficits and repetitive sensory–motor behaviours associated with a strong genetic component as well as other causes. The outlook for many individuals with autism spectrum disorder today is brighter than it was 50 years ago; more people with the condition are able to speak, read, and live in the community rather than in institutions, and some will be largely free from symptoms of the disorder by adulthood. Nevertheless, most individuals will not work full-time or live independently. Genetics and neuroscience have identified intriguing patterns of risk, but without much practical benefit yet. Considerable work is still needed to understand how and when behavioural and medical treatments can be effective, and for which children, including those with substantial comorbidities. It is also important to implement what we already know and develop services for adults with autism spectrum disorder. Clinicians can make a difference by providing timely and individualised help to families navigating referrals and access to community support systems, by providing accurate information despite often unfiltered media input, and by anticipating transitions such as family changes and school entry and leaving.
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            Does the chimpanzee have a theory of mind?

            An individual has a theory of mind if he imputes mental states to himself and others. A system of inferences of this kind is properly viewed as a theory because such states are not directly observable, and the system can be used to make predictions about the behavior of others. As to the mental states the chimpanzee may infer, consider those inferred by our own species, for example, purpose or intention , as well as knowledge, belief, thinking, doubt, guessing, pretending, liking , and so forth. To determine whether or not the chimpanzee infers states of this kind, we showed an adult chimpanzee a series of videotaped scenes of a human actor struggling with a variety of problems. Some problems were simple, involving inaccessible food – bananas vertically or horizontally out of reach, behind a box, and so forth – as in the original Kohler problems; others were more complex, involving an actor unable to extricate himself from a locked cage, shivering because of a malfunctioning heater, or unable to play a phonograph because it was unplugged. With each videotape the chimpanzee was given several photographs, one a solution to the problem, such as a stick for the inaccessible bananas, a key for the locked up actor, a lit wick for the malfunctioning heater. The chimpanzee's consistent choice of the correct photographs can be understood by assuming that the animal recognized the videotape as representing a problem, understood the actor's purpose, and chose alternatives compatible with that purpose.
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              Robust statistical methods in R using the WRS2 package

              This paper introduces the R package WRS2 that implements various robust statistical methods. It elaborates on the basics of robust statistics by introducing robust location, dispersion, and correlation measures. The location and dispersion measures are then used in robust variants of independent and dependent samples t tests and ANOVA, including between-within subject designs and quantile ANOVA. Further, robust ANCOVA as well as robust mediation models are introduced. The paper targets applied researchers; it is therefore kept rather non-technical and written in a tutorial style. Special emphasis is placed on applications in the social and behavioral sciences and illustrations of how to perform corresponding robust analyses in R. The R code for reproducing the results in the paper is given in the Supplementary Materials.
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                Author and article information

                Contributors
                URI : https://loop.frontiersin.org/people/2279735Role: Role: Role: Role: Role: Role:
                URI : https://loop.frontiersin.org/people/2734035Role: Role: Role: Role: Role: Role:
                URI : https://loop.frontiersin.org/people/597445Role: Role: Role: Role: Role: Role:
                URI : https://loop.frontiersin.org/people/266126Role: Role: Role: Role:
                Role: Role:
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                URI : https://loop.frontiersin.org/people/188331Role: Role:
                URI : https://loop.frontiersin.org/people/2726393Role: Role: Role: Role: Role:
                Journal
                Front Psychiatry
                Front Psychiatry
                Front. Psychiatry
                Frontiers in Psychiatry
                Frontiers Media S.A.
                1664-0640
                14 October 2024
                2024
                : 15
                : 1347913
                Affiliations
                [1] 1 Institute of German Studies, University of Duisburg-Essen , Duisburg, Germany
                [2] 2 Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg , Freiburg, Germany
                [3] 3 Department of Psychiatry and Psychotherapy, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg , Freiburg, Germany
                [4] 4 Luzerner Psychiatrie, Ambulante Dienste , Luzern, Switzerland
                [5] 5 Institute of Acoustics and Speech Communication, Technische Universität Dresden , Dresden, Germany
                Author notes

                Edited by: Antonio M. Persico, University of Modena and Reggio Emilia, Italy

                Reviewed by: Elisabetta Genovese, University of Modena and Reggio Emilia, Italy

                Loredana Schettino, Free University of Bozen-Bolzano, Italy

                Simon Betz, Bielefeld University, Germany

                *Correspondence: Charlotte Bellinghausen, charlotte.bellinghausen@ 123456uni-due.de
                Article
                10.3389/fpsyt.2024.1347913
                11513626
                39469475
                bc03bb61-77ee-45a4-bcdc-4b92525896e5
                Copyright © 2024 Bellinghausen, Schröder, Rauh, Riedel, Dahmen, Birkholz, Tebartz van Elst and Fangmeier

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 01 December 2023
                : 09 September 2024
                Page count
                Figures: 6, Tables: 7, Equations: 0, References: 118, Pages: 21, Words: 14533
                Funding
                The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. The study was funded by the “Programm zur Förderung des exzellenten wissenschaftlichen Nachwuchses” of the University of Duisburg-Essen. We acknowledge support by the Open Access Publication Fund of the University of Duisburg-Essen.
                Categories
                Psychiatry
                Original Research
                Custom metadata
                Autism

                Clinical Psychology & Psychiatry
                speech perception,autism spectrum disorder,prosody,uncertainty,emotion perception,theory of mind

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