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      Biometric Measurement of Anterior Segment: A Review

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          Biometric measurement of the anterior segment is of great importance for the ophthalmology, human eye modeling, contact lens fitting, intraocular lens design, etc. This paper serves as a comprehensive review on the historical development and basic principles of the technologies for measuring the geometric profiles of the anterior segment. Both the advantages and drawbacks of the current technologies are illustrated. For in vivo measurement of the anterior segment, there are two main challenges that need to be addressed to achieve high speed, fine resolution, and large range imaging. One is the motion artefacts caused by the inevitable and random human eye movement. The other is the serious multiple scattering effects in intraocular turbid media. The future research perspectives are also outlined in this paper.

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          Optical coherence tomography - principles and applications

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            Optical coherence tomography

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              Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography.

              To demonstrate a new diagnostic technique, optical coherence tomography, for high-resolution cross-sectional imaging of structures in the anterior segment of the human eye in vivo. Optical coherence tomography is a new, noninvasive, noncontact optical imaging modality that has spatial resolution superior to that of conventional clinical ultrasonography ( 90 dB). Survey of intraocular structure and dimension measurements. Laboratory. Convenience sample. Correlation with range of accepted normal intraocular structure profiles and dimensions. Direct in vivo measurements with micrometer-scale resolution were performed of corneal thickness and surface profile (including visualization of the corneal epithelium), anterior chamber depth and angle, and iris thickness and surface profile. Dense nuclear cataracts were successfully imaged through their full thickness in a cold cataract model in calf eyes in vitro. Optical coherence tomography has potential as a diagnostic tool for applications in noncontact biometry, anterior chamber angle assessment, identification and monitoring of intraocular masses and tumors, and elucidation of abnormalities of the cornea, iris, and crystalline lens.

                Author and article information

                Sensors (Basel)
                Sensors (Basel)
                Sensors (Basel, Switzerland)
                31 July 2020
                August 2020
                : 20
                : 15
                [1 ]Tianjin Key Laboratory for Control Theory & Applications in Complicated Systems, Tianjin University of Technology, Tianjin 300384, China; lbin83@ 123456126.com
                [2 ]Centre of Micro/Nano manufacturing Technology (MNMT-Dublin), University College Dublin, D04 V1W8 Dublin 4, Dublin, Ireland; chengwei.kang@ 123456ucd.ie
                [3 ]State Key Laboratory of Precision Measuring Technology and Instruments, Centre of Micro/Nano Manufacturing Technology (MNMT), Tianjin University, Tianjin 300372, China
                Author notes
                [* ]Correspondence: fengzhou.fang@ 123456ucd.ie ; Tel.: +353-1-716-1810
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).


                Biomedical engineering

                anterior segment, geometric measurement, corneal topography, tomography


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