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      Development of Light Dissemination in the Rat Lens after in vivo Exposure to Radiation in the 300-nm Wavelength Region

      Ophthalmic Research

      S. Karger AG

      Ultraviolet radiation, Rat lens, Cataract, Light dissemination

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          The course of development of light dissemination was investigated for rat lenses exposed in vivo to 30 kJ/m<sup>2</sup> ultraviolet radiation (UVR) in the 300-nm wavelength region After an initial latency phase the light dissemination increases rapidly. At 72 h after the exposure to UVR, light dissemination almost reaches a maximum. An exponential model is proposed for the analysis of this pattern. Light dissemination also increases in lenses contralateral to exposed. This indicates that there may be a systemic reponse after exposure to UVR which can lead to cataract formation.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          10 December 2009
          : 22
          : 5
          : 271-279
          Department of Ophthalmology (Head: Björn Tengroth) and Department of Medical Biophysics (Head: Rudolf Rigler), Karolinska Institute, Stockholm, Sweden
          267035 Ophthalmic Res 1990;22:271–279
          © 1990 S. Karger AG, Basel

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          Page count
          Pages: 9


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