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      Development of Light Dissemination in the Rat Lens after in vivo Exposure to Radiation in the 300-nm Wavelength Region

      Ophthalmic Research

      S. Karger AG

      Ultraviolet radiation, Rat lens, Cataract, Light dissemination

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          Abstract

          The course of development of light dissemination was investigated for rat lenses exposed in vivo to 30 kJ/m<sup>2</sup> ultraviolet radiation (UVR) in the 300-nm wavelength region After an initial latency phase the light dissemination increases rapidly. At 72 h after the exposure to UVR, light dissemination almost reaches a maximum. An exponential model is proposed for the analysis of this pattern. Light dissemination also increases in lenses contralateral to exposed. This indicates that there may be a systemic reponse after exposure to UVR which can lead to cataract formation.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1990
          1990
          10 December 2009
          : 22
          : 5
          : 271-279
          Affiliations
          Department of Ophthalmology (Head: Björn Tengroth) and Department of Medical Biophysics (Head: Rudolf Rigler), Karolinska Institute, Stockholm, Sweden
          Article
          267035 Ophthalmic Res 1990;22:271–279
          10.1159/000267035
          2090981
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
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          Paper

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