Invasive versus conservative strategy in patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris (After Eighty study): an open-label randomised controlled trial.

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Abstract

Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina pectoris are frequent causes of hospital admission in the elderly. However, clinical trials targeting this population are scarce, and these patients are less likely to receive treatment according to guidelines. We aimed to investigate whether this population would benefit from an early invasive strategy versus a conservative strategy.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Mar 12 2016

Volume: 387

Issue: 10023

Affiliations

[1 ] Department of Cardiology, Oslo University Hospital, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway.

[2 ] Centre for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway; Centre for Clinical Heart Research, Oslo University Hospital, Oslo, Norway.

[3 ] Department of Cardiology, Oslo University Hospital, Oslo, Norway.

[4 ] Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Cardiology, Akershus University Hospital, Lørenskog, Norway.

[5 ] Department of Cardiology, Drammen Hospital, Drammen, Norway.

[6 ] Department of Cardiology, Lillehammer Hospital, Lillehammer, Norway.

[7 ] Diakonhjemmet Hospital and Department of Clinical Science, University of Bergen, Bergen, Norway.

[8 ] Department of Cardiology, Oslo University Hospital, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address: bbendz@ous-hf.no.

Article

Publisher Item ID: S0140-6736(15)01166-6

DOI: 10.1016/S0140-6736(15)01166-6

PubMed ID: 26794722

SO-VID: bc1bfbf0-16c6-4d75-af9a-f487e6e0ed54

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