Accurate dosimetry in 131I radionuclide therapy using patient-specific, 3-dimensional methods for SPECT reconstruction and absorbed dose calculation.

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Abstract

(131)I radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity quantification and dose estimation. The goal of this work was to establish the accuracy of (131)I activity quantification and absorbed dose estimation when patient-specific, 3-dimensional (3D) methods are used for SPECT reconstruction and for absorbed dose calculation.

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Journal

Journal ID (iso-abbrev): J. Nucl. Med.

Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

ISSN: 0161-5505

ISSN (Print): 0161-5505

Publication date (Electronic): May 2005

Volume: 46

Issue: 5

Affiliations

[1 ] Division of Nuclear Medicine, Department of Radiology, The University of Michigan Medical Center, 204 Zina Pitcher Place, Ann Arbor, MI 48109-0552, USA. yuni@umich.edu

Article

Publisher Item ID: 46/5/840 Mid ID: NIHMS164571

PMC ID: 2804106

PubMed ID: 15872359

SO-VID: bc743ee7-e8b0-4db2-bd4c-b2e9c74710a5

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