Objective To describe the epidemiological characteristics and clinical manifestations of the 2019 coronavirus disease (COVID-19) in pediatric patients, and to provide data support and decision-making basis for the prevention and control of COVID-19.
Methods Cases of children aged 0-17 years reported by provincial health commissions in Anhui, Shandong, Zhejiang and Henan provinces were collected to analyze their spatial, temporal, and demographic distribution.
Resluts By 24: 00 on February 6, 2020, a total of 107 pediatric patients had been reported in the four provinces, accounting for 3.8% (107/2 808) of the total cases reported in the four provinces during the same period. Anhui, Shandong, Zhejiang and Henan provinces had 25, 25, 28 and 29 cases, respectively. Cases ranged in age from 5 days after birth to 17 years, with a median age of 8 years. Boys accounted for 58.9%. Totally 38 cases had a history of sojourn in Wuhan or Hubei, 63 cases had a history of exposure to conlinned cases, and 6 cases with unknown exposure history. A group of 52 family clustering were found in 107 cases. All cases presented mild symptoms, no serious and no death.
Conclusion Children were also susceptible to the COVID-19. Before February 2, the index pediatric cases were mainly the first generation cases, and after February 3, these pediatric cases were mainly the secondary-generation cases and those who had close contact with confirmed cases. The monitoring of children with second-generation cases and close contact with COVID-19 cases were valued.
【摘要】 目的探讨新型冠状病毒肺炎 (以下简称“新冠肺炎”) 儿童病例的流行病学特征和临床表现, 为防控新冠 肺炎提供数据支持和决策依据。 方法 以安徽省、山东省、浙江省和河南省省级卫生健康委员会报告的中国内地0~ 17岁 儿童病例为研究对象, 分析其时间、空间和人群分布等流行病学特征。 结果 截至2020年2月6日24:00, 4省共报告107 例儿童病例, 占4省同期报告总病例数的3.8% (107/2 808), 其中安徽省、山东省、浙江省和河南省分别为25, 25, 28和29 例。病例的年龄范围为生后5 d~17岁, 年龄中位数为8岁, 男童占比为58.9%。确诊病例中0~4岁29例 (27.1%), 5~9 岁32例 (30.0%), 10~14岁24例 (22.4%), 15 ~ 17岁22例 (20.5%)。38例有武汉或湖北旅居史, 63例有确诊病例接触 史, 6例暴露史不明。107例中共发现52起家庭聚集性病例。目前所有病例症状均表现轻微, 无重症和死亡病例。2月2 日前首发病例有武汉或湖北旅居史的比例高于2月3日及以后首发病例(X 2 = 6.38, P<0.05)。 结论 新冠肺炎早期的儿童 病例亦是新冠肺炎易感人群, 而且2月2日前以一代病例为主, 2月3日后以二代病例及密切接触者为主。应重视二代病 例和有密切接触史儿童的监护。