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      Antibiotics from basidiomycetes. XVIII. Strobilurin C and oudemansin B, two new antifungal metabolites from Xerula species (Agaricales).

      The Journal of antibiotics

      Acrylates, isolation & purification, Agaricales, analysis, growth & development, Antifungal Agents, Basidiomycota, Circular Dichroism, Fatty Acids, Unsaturated, Fermentation, Fungi, drug effects, Magnetic Resonance Spectroscopy, Mass Spectrometry, Methacrylates, Microbial Sensitivity Tests, Spectrophotometry, Valerates

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          Abstract

          Two new antifungal (E)-beta-methoxyacrylates, strobilurin C and oudemansin B, were isolated from cultures of Xerula longipes and Xerula melanotricha. Their structures were elucidated by spectroscopic methods. Both antibiotics inhibit the growth of a wide variety of saprophytic and phytopathogenic fungi at very low concentrations. Like strobilurins A, B, and oudemansin A the new metabolites are potent inhibitors of respiration.

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          6874589

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