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      Does N-cadherin regulate interaction of hematopoietic stem cells with their niches?

      Cell Stem Cell

      physiology, Osteoblasts, Mice, cytology, Hematopoietic Stem Cells, Cell Adhesion, genetics, biosynthesis, Cadherins, Animals

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          Abstract

          In this issue of Cell Stem Cell, Kiel et al. (2007) demonstrate that N-cadherin is not expressed on repopulating hematopoietic stem cells (HSCs) and that reduction of osteoblasts does not affect HSC frequency, suggesting that other molecular pathways may also modulate the interaction of HSCs with their niches.

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          Journal
          10.1016/j.stem.2007.07.012
          2951616
          18371341

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