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      Assessing Cardiac Function by Gas Exchange

      ,

      Cardiology

      S. Karger AG

      O2 uptake, Pulmonary gas exchange, Anaerobic threshold, Exercise, Cellular respiration, Lactic acid

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          Abstract

          Exercise stresses the primary function of the cardiovascular system, which is the supply of O<sub>2</sub> and removal of CO<sub>2</sub> from the cells of the body. Even ordinary walking requires an increase in O<sub>2</sub> consumption and CO<sub>2</sub> production by the exercising muscles of 20 times the resting level. While pulmonary dysfunction may affect arterial blood gas tensions, the dynamics of O<sub>2</sub> uptake and CO<sub>2</sub> output by the lungs depend on the circulatory responses to exercise. Thus, measurement of the dynamics of O<sub>2</sub> uptake in response to exercise has been shown to reflect cardiovascular function. Inability of the circulatory responses to meet an increased O<sub>2</sub> requirement may be reflected in abnormalities in O<sub>2</sub> uptake dynamics, and an early increase in CO<sub>2</sub> output relative to O<sub>2</sub> uptake consequent to bicarbonate buffering of lactic acid. Application of currently available technology for the continuous measurement and analysis of pulmonary gas exchange can afford the practicing or investigative cardiologist with a noninvasive and inexpensive means for assessing cardiovascular function.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1988
          1988
          11 November 2008
          : 75
          : 4
          : 307-310
          Affiliations
          Division of Respiratory and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center, Torrance, Calif., USA
          Article
          174390 Cardiology 1988;75:307–310
          10.1159/000174390
          3048668
          © 1988 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Exercise Testing and Rehabilitation

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