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      Investigación clínica a pie de cama. Sepsis Translated title: Recerca clínica a peu de llit. Sèpsia Translated title: Clinical research at the bedside. Sepsis

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Resumen La investigación clínica en sepsis es una prioridad y una obligación cuyo objetivo primordial ha de ser tanto el conocimiento de su compleja fisiopatología como la búsqueda de herramientas diagnósticas precoces y eficaces, para mejorar el tratamiento y disminuir la tasa de mortalidad. Los principios éticos de la investigación biomédica ayudan a determinar el equilibrio entre el avance de la ciencia y la protección de los derechos y bienestar de los sujetos de la investigación.

          Translated abstract

          Resum La recerca clínica en la sèpsia és una prioritat i una obligació l'objectiu primordial de la qual ha de ser tant el coneixement de la seva complexa fisiopatología, com la cerca d'eines diagnòstiques precoces i eficaces per a millorar-ne el tractament i disminuir la taxa de mortalitat. Els principis ètics de la recerca biomèdica ajuden a determinar l'equilibri entre l'avanç de la ciència i la protecció dels drets i benestar dels subjectes de la recerca.

          Translated abstract

          Abstract Clinical research in sepsis is a priority and an obligation whose primary objective must be both knowledge of its complex pathophysiology and the search for early and effective diagnostic tools to improve treatment and reduce the mortality rate. The ethical principles of biomedical research help to determine the balance between the advancement of science and the protection of the rights and welfare of research subjects.

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          Most cited references5

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          Código ético de la Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias (SEMICYUC)

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            A history of ethics and law in the intensive care unit.

            Because they provide potential benefit at great personal and public cost, the intensive care unit (ICU) and the interventions rendered therein have become symbols of both the promise and the limitations of medical technology. At the same time, the ICU has served as an arena in which many of the ethical and legal dilemmas created by that technology have been defined and debated. This article outlines major events in the history of ethics and law in the ICU, covering the evolution of ICUs, ethical principles, informed consent and the law, medical decision-making, cardiopulmonary resuscitation, withholding and withdrawing life-sustaining therapy, legal cases involving life support, advance directives, prognostication, and futility and the allocation of medical resources. Advancement of the ethical principle of respect for patient autonomy in ICUs increasingly is in conflict with physicians' concern about their own prerogatives and with the just distribution of medical resources.
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              The third international consensus definitions for sepsis and septic

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                Author and article information

                Journal
                bioetica
                Revista de Bioética y Derecho
                Rev. Bioética y Derecho
                Observatori de Bioètica i Dret - Cátedra UNESCO de Bioética (Barcelona, Barcelona, Spain )
                1886-5887
                2020
                : 48
                : 127-137
                Affiliations
                [2] Barcelona orgnameHospital de Sant Pau orgdiv1Servicio de Medicina Intensiva Spain
                [1] Barcelona orgnameHospital de Barcelona-SCIAS orgdiv1Servicio de Medicina Intensiva Spain
                Article
                S1886-58872020000100009 S1886-5887(20)00004800009
                bd717ce7-729d-4a00-ba09-bb86fec43f33

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 01 October 2019
                : 26 August 2019
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 10, Pages: 11
                Product

                SciELO Spain

                Categories
                Dossier Bioética y Medicina Intensiva

                sepsis,Ètica en recerca clínica,sèpsia,Ethics in clinical research,Ética en investigación clínica

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