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      Sarcoidosis of the Hypothalamus

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      Hormone Research in Paediatrics

      S. Karger AG

      Man, Hypothalamus, Sarcoidosis

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          A case of hypothalamic sarcoidosis with autopsy findings is recorded. This case and 18 others from the literature with evidence of a sarcoid lesion in the hypothalamus at autopsy are analysed. The symptoms and signs attributed to secondary disturbance of the endocrine system are much less striking and less diagnostic than those attributed to involvement of other centres in the hypothalamus. In the case recorded, the hyper-somnolence could be attributed to hypothermia. The gross striae was a striking feature and their distribution differed from those seen in Cushing’s syndrome. The electrolyte disturbances were varied and the occurrence of hyponatraemia or hypochloraemia has not been previously reported.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          21 November 2008
          : 2
          : 1
          : 1-12
          St. Vincent’s Hospital and Department of Medicine and Therapeutics, University College, Dublin
          178220 Hormones 1971;2:1–12
          © 1971 S. Karger AG, Basel

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          Page count
          Pages: 12


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