Time and cost of maxillofacial prosthetic treatment: The need for assessment

Medication-related osteonecrosis of the jaw (MRONJ) can be triggered by several antiresorptive and antiangiogenic medications, including bisphosphonates (BRONJ), denosumab (DRONJ), and other agents used to treat osteoporosis and metastatic bone cancer. Prosthodontists and surgeons continue to face new challenges because of this condition. Despite the current evidence showing that extensive surgical intervention and laser surgery have the highest healing rates, surgical reconstruction is not always possible for large jaw defects requiring prosthetic reconstruction. Moreover, surgical treatment may not be an option in some patients because of other medical conditions. In these patients, MRONJ may develop into a chronic disease with limited resolution and they may seek prosthetic rehabilitation for aesthetic and functional reasons. Therefore, prosthetic intervention may be necessary for some patients with MRONJ even in the absence of a surgical defect. Denture trauma has been reported to be a risk factor for MRONJ, and few reports have discussed the prosthodontic considerations needed for patients with this condition. The aim of this review is to highlight the prosthodontic considerations that would decrease the risk of triggering MRONJ in susceptible patients.

'The face is the mirror of the mind', so said St Jerome. Patients affected by head and neck cancer have to deal not only with the effects of the disease but also with the effects of the treatment for the disease. This is one cancer which is literally and figuratively 'in your face'! And it is a disease which is difficult to hide. This article attempts to summarise head and neck cancer and its treatment modalities as well as the effects of treatment and the defects it creates. It will also attempt to explore and elaborate on the novel prosthodontic management techniques in advanced jaw reconstruction and extraoral anatomical defects. The concept of functional assessment and rehabilitation in head and neck cancer patient management will also be briefly explained.