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      The Low Countries – 16th/17th Century

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          Abstract

          Andreas Vesalius and Jan Baptist Van Helmont are the two major personalities who contributed substantially and in a different way to the early development of renal anatomy/physiology of the 16th/17th century in the Southern Low Countries. The importance of A. Vesalius’ publication ‘de humani corporis fabrica libri septem’ cannot be overestimated. The kidney was an intriguing organ to Vesalius, the function of which he could not fully grasp. J.B. Van Helmont was the first to demonstrate the importance of the measurement of the specific gravity of the urine and relating it to physiological and pathophysiological conditions. He made accurate clinical observations supported by autopsy examinations concerning the role of the kidney in the generation of dropsy.

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          Author and article information

          Journal
          AJN
          Am J Nephrol
          10.1159/issn.0250-8095
          American Journal of Nephrology
          S. Karger AG
          978-3-8055-6855-5
          978-3-318-00128-0
          0250-8095
          1421-9670
          1999
          April 1999
          23 April 1999
          : 19
          : 2
          : 282-289
          Affiliations
          Departments of aNephrology and bExperimental Surgery, University of Antwerp, and cZeneca Pharma, Ghent,Belgium
          Article
          13462 Am J Nephrol 1999;19:282–289
          10.1159/000013462
          10213829
          © 1999 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Figures: 10, References: 8, Pages: 8
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/13462
          Categories
          Origins of Renal Physiology (Dedicated to Carl Gottschalk)

          Cardiovascular Medicine, Nephrology

          Urine analysis, Edema, Vesalius, Van Helmont

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