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      Variable anisotropic FOV for 3D radial imaging with spiral phyllotaxis (VASP)

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          Abstract

          Purpose

          To develop a new 3D radial trajectory based on the natural spiral phyllotaxis (SP), with variable anisotropic FOV.

          Theory & Methods

          A 3D radial trajectory based on the SP with favorable interleaving properties for cardiac imaging has been proposed by Piccini et al ( Magn Reson Med. 2011;66:1049‐1056), which supports a FOV with a fixed anisotropy. However, a fixed anisotropy can be inefficient when sampling objects with different anisotropic dimensions. We extend Larson’s 3D radial method to provide variable anisotropic FOV for spiral phyllotaxis (VASP). Simulations were performed to measure distance between successive projections, analyze point spread functions, and compare aliasing artifacts for both VASP and conventional SP. VASP was fully implemented on a whole‐body clinical MR scanner. Phantom and in vivo cardiac images were acquired at 1.5 tesla.

          Results

          Simulations, phantom, and in vivo experiments confirmed that VASP can achieve variable anisotropic FOV while maintaining the favorable interleaving properties of SP. For an anisotropic FOV with 100:100:35 ratio, VASP required ~65% fewer radial projections than the conventional SP to satisfy Nyquist criteria. Alternatively, when the same number of radial projections were used as in conventional SP, VASP produced fewer aliasing artifacts for anisotropic objects within the excited imaging volumes.

          Conclusion

          We have developed a new method (VASP), which enables variable anisotropic FOV for 3D radial trajectory with SP. For anisotropic objects within the excited imaging volumes, VASP can reduce scan times and/or reduce aliasing artifacts.

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          Most cited references27

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          An optimal radial profile order based on the Golden Ratio for time-resolved MRI.

          In dynamic magnetic resonance imaging (MRI) studies, the motion kinetics or the contrast variability are often hard to predict, hampering an appropriate choice of the image update rate or the temporal resolution. A constant azimuthal profile spacing (111.246 degrees), based on the Golden Ratio, is investigated as optimal for image reconstruction from an arbitrary number of profiles in radial MRI. The profile order is evaluated and compared with a uniform profile distribution in terms of signal-to-noise ratio (SNR) and artifact level. The favorable characteristics of such a profile order are exemplified in two applications on healthy volunteers. First, an advanced sliding window reconstruction scheme is applied to dynamic cardiac imaging, with a reconstruction window that can be flexibly adjusted according to the extent of cardiac motion that is acceptable. Second, a contrast-enhancing k-space filter is presented that permits reconstructing an arbitrary number of images at arbitrary time points from one raw data set. The filter was utilized to depict the T1-relaxation in the brain after a single inversion prepulse. While a uniform profile distribution with a constant angle increment is optimal for a fixed and predetermined number of profiles, a profile distribution based on the Golden Ratio proved to be an appropriate solution for an arbitrary number of profiles.
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            The NMR phased array

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              Ultrashort echo time imaging using pointwise encoding time reduction with radial acquisition (PETRA).

              Sequences with ultrashort echo times enable new applications of MRI, including bone, tendon, ligament, and dental imaging. In this article, a sequence is presented that achieves the shortest possible encoding time for each k-space point, limited by pulse length, hardware switching times, and gradient performance of the scanner. In pointwise encoding time reduction with radial acquisition (PETRA), outer k-space is filled with radial half-projections, whereas the centre is measured single pointwise on a Cartesian trajectory. This hybrid sequence combines the features of single point imaging with radial projection imaging. No hardware changes are required. Using this method, 3D images with an isotropic resolution of 1 mm can be obtained in less than 3 minutes. The differences between PETRA and the ultrashort echo time (UTE) sequence are evaluated by simulation and phantom measurements. Advantages of pointwise encoding time reduction with radial acquisition are shown for tissue with a T(2) below 1 ms. The signal to noise ratio and Contrast-to-noise ratio (CNR) performance, as well as possible limitations of the approach, are investigated. In-vivo head, knee, ankle, and wrist examples are presented to prove the feasibility of the sequence. In summary, fast imaging with ultrashort echo time is enabled by PETRA and may help to establish new routine clinical applications of ultrashort echo time sequences.
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                Author and article information

                Contributors
                guruprasad.krishnamoorthy@philips.com
                Journal
                Magn Reson Med
                Magn Reson Med
                10.1002/(ISSN)1522-2594
                MRM
                Magnetic Resonance in Medicine
                John Wiley and Sons Inc. (Hoboken )
                0740-3194
                1522-2594
                27 August 2020
                January 2021
                : 85
                : 1 ( doiID: 10.1002/mrm.v85.1 )
                : 68-77
                Affiliations
                [ 1 ] Department of MR R&D–Clinical Science Philips, Best The Netherlands
                [ 2 ] Department of Biomedical Engineering Eindhoven University of Technology Eindhoven The Netherlands
                Author notes
                [*] [* ] Correspondence

                Guruprasad Krishnamoorthy, Department of MR R&D–Clinical Science, Philips, Veenpluis 4‐6, 5684 PC, Best, The Netherlands.

                Email: guruprasad.krishnamoorthy@ 123456philips.com

                Author information
                https://orcid.org/0000-0003-0578-8645
                https://orcid.org/0000-0002-1388-4023
                Article
                MRM28449
                10.1002/mrm.28449
                7692914
                32851711
                be53607c-8adb-4909-9129-aca3c5c14505
                © 2020 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 30 November 2019
                : 30 May 2020
                : 08 July 2020
                Page count
                Figures: 7, Tables: 0, Pages: 8, Words: 9549
                Funding
                Funded by: H2020 Marie Skłodowska‐Curie Actions
                Award ID: project number 642458
                Categories
                Rapid Communication
                Rapid Communication—Imaging Methodology
                Custom metadata
                2.0
                January 2021
                Converter:WILEY_ML3GV2_TO_JATSPMC version:5.9.4 mode:remove_FC converted:27.11.2020

                Radiology & Imaging
                Radiology & Imaging

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