Co-administration of transient receptor potential vanilloid 4 (TRPV4) and TRPV1 antagonists potentiate the effect of each drug in a rat model of cystitis.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

To investigate transient receptor potential vanilloid 4 (TRPV4) expression in bladder afferents and study the effect of TRPV4 and TRPV1 antagonists, alone and in combination, in bladder hyperactivity and pain induced by cystitis.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): BJU Int.

Title: BJU international

ISSN (Electronic): 1464-410X

ISSN (Print): 1464-4096

Publication date (Electronic): Mar 2015

Volume: 115

Issue: 3

Affiliations

[1 ] Department of Renal, Urologic and Infectious Disease, Porto, Portugal; Department of Experimental Biology, Faculty of Medicine of the University of Porto, Porto, Portugal; IBMC - Instituto de Biologia Molecular e Celular da Universidade do Porto, Porto, Portugal.

Article

DOI: 10.1111/bju.12861

PubMed ID: 25041193

SO-VID: beb96ec4-60a2-4951-811a-40af74106a97

History

Keywords: TRPV1 antagonist,TRPV4 antagonist,cystitis,lower urinary tract

Data availability:

Keywords: TRPV1 antagonist, TRPV4 antagonist, cystitis, lower urinary tract

Comments

Comment on this article

scite_

Cited by 9

See all cited by