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      Perioperative Duloxetine to Improve Postoperative Recovery After Abdominal Hysterectomy: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study.

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          Abstract

          Postsurgical quality of recovery is worse in female than that in male patients. Duloxetine has been used successfully for the treatment of chronic pain conditions, but its use for preventing acute postoperative pain has been limited to a single previous study. More importantly, the effect of preoperative duloxetine on global postoperative quality of recovery has yet to be evaluated. The main objective of the current investigation was to evaluate the effect of perioperative duloxetine on postoperative quality of recovery in women undergoing abdominal hysterectomy.

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          Author and article information

          Journal
          Anesth. Analg.
          Anesthesia and analgesia
          Ovid Technologies (Wolters Kluwer Health)
          1526-7598
          0003-2999
          Jan 2016
          : 122
          : 1
          Affiliations
          [1 ] From the *Department of Anesthesiology, Santo Antonio Hospital, Salvador, Bahia, Brazil; †Botucatu Medical School, Botucatu, Sao Paulo, Brazil; and ‡Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
          Article
          10.1213/ANE.0000000000000971
          26421810

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