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      Quantification of growth factors in advanced platelet‐rich fibrin and concentrated growth factors and their clinical efficacy as adjunctive to the GTR procedure in periodontal intrabony defects

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          Bone regeneration in the maxillary sinus using an autologous fibrin-rich block with concentrated growth factors alone.

          The purpose of this study was to evaluate the predictability of new bone formation in the maxillary sinus using an autologous fibrin-rich blocks with concentrated growth factors (CGFs) alone as an alternative to graft material. A total of sixty-one sinus grafts were consecutively performed using the lateral window approach. After making replaceable bony window, the sinus membrane was elevated to make a new compartment. After 113 implants (average 13 mm high) with 11 different systems were placed simultaneously, the collected fibrin-rich blocks with CGFs alone were inserted in the sinus. To seal the lateral window, the bony window was repositioned. Radiographic, clinical, and histologic evaluation was performed to verify sinus augmentation. No significant postoperative complications developed. New bone consolidation in all augmented maxillary sinus was observed along the implants on plain radiographs and on cone-beam computed tomograms. The success rate of implant was 98.2% after an average of 10 months loading. Fibrin-rich blocks with CGFs act as an alternative to bone grafting and can be a predictable procedure for sinus augmentation.
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            The use of concentrated growth factors (CGF) for sinus augmentation

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              An opportunity in paroimplantology: PRF

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                Author and article information

                Contributors
                Journal
                Journal of Periodontology
                J Periodontol
                Wiley
                0022-3492
                1943-3670
                April 2020
                November 17 2019
                April 2020
                : 91
                : 4
                : 462-472
                Affiliations
                [1 ]Department of PeriodonticsSecond Affiliated HospitalSchool of MedicineZhejiang University Hangzhou China
                [2 ]Dental DepartmentSir Run Run Shaw HospitalSchool of MedicineZhejiang University Hangzhou China
                Article
                10.1002/JPER.19-0290
                31471902
                bed3cc70-38c4-4092-8eb5-84067ba9a3fb
                © 2020

                http://onlinelibrary.wiley.com/termsAndConditions#vor

                http://doi.wiley.com/10.1002/tdm_license_1.1

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