Each year, the American Cancer Society estimates the number of new cancer cases and
deaths expected in the United States in the current year and compiles the most recent
data on cancer incidence, mortality, and survival based on incidence data from the
National Cancer Institute, Centers for Disease Control and Prevention, and the North
American Association of Central Cancer Registries and mortality data from the National
Center for Health Statistics. Incidence and death rates are age-standardized to the
2000 US standard million population. A total of 1,437,180 new cancer cases and 565,650
deaths from cancer are projected to occur in the United States in 2008. Notable trends
in cancer incidence and mortality include stabilization of incidence rates for all
cancer sites combined in men from 1995 through 2004 and in women from 1999 through
2004 and a continued decrease in the cancer death rate since 1990 in men and since
1991 in women. Overall cancer death rates in 2004 compared with 1990 in men and 1991
in women decreased by 18.4% and 10.5%, respectively, resulting in the avoidance of
over a half million deaths from cancer during this time interval. This report also
examines cancer incidence, mortality, and survival by site, sex, race/ethnicity, education,
geographic area, and calendar year, as well as the proportionate contribution of selected
sites to the overall trends. Although much progress has been made in reducing mortality
rates, stabilizing incidence rates, and improving survival, cancer still accounts
for more deaths than heart disease in persons under age 85 years. Further progress
can be accelerated by supporting new discoveries and by applying existing cancer control
knowledge across all segments of the population.