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      Adult Bone Marrow Cell Therapy for Ischemic Heart Disease: Evidence and Insights From Randomized Controlled Trials.

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          Abstract

          Notwithstanding the uncertainties about the outcomes of bone marrow cell (BMC) therapy for heart repair, further insights are critically needed to improve this promising approach.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Circ. Res.
          Title: Circulation research
          ISSN (Electronic): 1524-4571
          ISSN (Print): 0009-7330
          Publication date (Electronic): Aug 28 2015
          Volume: 117
          Issue: 6
          Affiliations
          [1 ] From the Division of Cardiovascular Diseases, Cardiovascular Research Institute, and the Midwest Stem Cell Therapy Center, University of Kansas Medical Center, Kansas City (M.R.A., A.S., Z.I.S., B.D.); Heart and Vascular Specialists of Oklahoma, Oklahoma City (V.J.); Division of Cardiology, University of Kentucky, Lexington (A.A.-L.); and Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland (E.K.Z.-S).
          [2 ] From the Division of Cardiovascular Diseases, Cardiovascular Research Institute, and the Midwest Stem Cell Therapy Center, University of Kansas Medical Center, Kansas City (M.R.A., A.S., Z.I.S., B.D.); Heart and Vascular Specialists of Oklahoma, Oklahoma City (V.J.); Division of Cardiology, University of Kentucky, Lexington (A.A.-L.); and Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland (E.K.Z.-S). bdawn@kumc.edu.
          Article
          Publisher Item ID: CIRCRESAHA.114.304792 Mid ID: NIHMS707178
          DOI: 10.1161/CIRCRESAHA.114.304792
          PMC ID: 4553075
          PubMed ID: 26160853
          SO-VID: bef25edd-828d-4a63-8955-9b9b3f3b70f3
          Copyright © © 2015 American Heart Association, Inc.
          History

          Keywords: bone marrow mononuclear cells,meta-analysis,myocardial infarction,myocardial ischemia,stem cells
          Data availability:
          Keywords: bone marrow mononuclear cells, meta-analysis, myocardial infarction, myocardial ischemia, stem cells

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