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      Essential Oils of Oregano: Biological Activity beyond Their Antimicrobial Properties

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          Abstract

          Essential oils of oregano are widely recognized for their antimicrobial activity, as well as their antiviral and antifungal properties. Nevertheless, recent investigations have demonstrated that these compounds are also potent antioxidant, anti-inflammatory, antidiabetic and cancer suppressor agents. These properties of oregano essential oils are of potential interest to the food, cosmetic and pharmaceutical industries. The aim of this manuscript is to review the latest evidence regarding essential oils of oregano and their beneficial effects on health.

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          Origin and physiological roles of inflammation.

          Ruslan Medzhitov (2008)
          Inflammation underlies a wide variety of physiological and pathological processes. Although the pathological aspects of many types of inflammation are well appreciated, their physiological functions are mostly unknown. The classic instigators of inflammation - infection and tissue injury - are at one end of a large range of adverse conditions that induce inflammation, and they trigger the recruitment of leukocytes and plasma proteins to the affected tissue site. Tissue stress or malfunction similarly induces an adaptive response, which is referred to here as para-inflammation. This response relies mainly on tissue-resident macrophages and is intermediate between the basal homeostatic state and a classic inflammatory response. Para-inflammation is probably responsible for the chronic inflammatory conditions that are associated with modern human diseases.
          Article 0 comments Cited 1763 times – based on 0 reviews     Review now
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            Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review

            Maria Graça Miguel (2010)
            Essential oils are complex mixtures isolated from aromatic plants which may possess antioxidant and anti-inflammatory activities of interest in thye food and cosmetic industries as well as in the human health field. In this work, a review was done on the most recent publications concerning their antioxidant and anti-inflammatory activities. At the same time a survey of the methods generally used for the evaluation of antioxidant activity and some of the mechanisms involved in the anti-inflammatory activities of essential oils are also reported.
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              Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems

              Javad Sharifi-Rad, Antoni Sureda, Gian Carlo Tenore … (2017)
              Essential oils are complex mixtures of hydrocarbons and their oxygenated derivatives arising from two different isoprenoid pathways. Essential oils are produced by glandular trichomes and other secretory structures, specialized secretory tissues mainly diffused onto the surface of plant organs, particularly flowers and leaves, thus exerting a pivotal ecological role in plant. In addition, essential oils have been used, since ancient times, in many different traditional healing systems all over the world, because of their biological activities. Many preclinical studies have documented antimicrobial, antioxidant, anti-inflammatory and anticancer activities of essential oils in a number of cell and animal models, also elucidating their mechanism of action and pharmacological targets, though the paucity of in human studies limits the potential of essential oils as effective and safe phytotherapeutic agents. More well-designed clinical trials are needed in order to ascertain the real efficacy and safety of these plant products.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Molecules
                Journal ID (iso-abbrev): Molecules
                Journal ID (publisher-id): molecules
                Title: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
                Publisher: MDPI
                ISSN (Electronic): 1420-3049
                Publication date (Electronic): 14 June 2017
                Publication date Collection: June 2017
                Volume: 22
                Issue: 6
                Electronic Location Identifier: 989
                Affiliations
                Centro de Investigación en Alimentación y Desarrollo A.C., Carretera a El Dorado km 5.5 Col. El Diez C.P., Culiacán, Sinaloa 80129, Mexico; nayely061005@ 123456gmail.com (N.L.-L.); erickpaulggrijalva@ 123456gmail.com (E.P.G.-G.); vazquezgabriela18@ 123456gmail.com (G.V.-O.)
                Author notes
                [* ]Correspondence: jbheredia@ 123456ciad.mx ; Tel.: +52-166-776-05536
                Article
                Publisher ID: molecules-22-00989
                DOI: 10.3390/molecules22060989
                PMC ID: 6152729
                PubMed ID: 28613267
                SO-VID: bef5fdb3-8d1b-45ca-b5f3-17364b19fb32
                Copyright © © 2017 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 25 May 2017
                Date accepted : 10 June 2017
                Categories
                Subject: Review

                Keywords: oregano species,terpenoids,antioxidant,anti-inflammatory,antidiabetic
                Data availability:
                Keywords: oregano species, terpenoids, antioxidant, anti-inflammatory, antidiabetic

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