The impact of frailty on coagulation and responses to warfarin in acute older hospitalised patients with atrial fibrillation: a pilot study.

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Abstract

The evidence on coagulation changes with frailty is not consistent and clinical studies suggest that frail older people may be at an increased risk of bleeding complications with anticoagulant therapy.

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Author and article information

Journal

Journal ID (iso-abbrev): Aging Clin Exp Res

Title: Aging clinical and experimental research

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1720-8319

ISSN (Print): 1594-0667

Publication date (Electronic): Dec 2017

Volume: 29

Issue: 6

Affiliations

[1 ] Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital and Kolling Institute of Medical Research, Sydney Medical School, University of Sydney, Sydney, NSW, Australia. nngu9517@uni.sydney.edu.au.

[2 ] Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia. nngu9517@uni.sydney.edu.au.

[3 ] Department of Haematology and Transfusion Medicine, Royal North Shore Hospital and Northern Blood Research Centre, Kolling Institute of Medical Research, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.

[4 ] Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia.

[5 ] Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital and Kolling Institute of Medical Research, Sydney Medical School, University of Sydney, Sydney, NSW, Australia. sarah.hilmer@sydney.edu.au.