Abstract: Objective: Our experiment was undertaken to explore the positive effects of taurine (Tau) on the redox system and essential elements in the kidney of aluminum (Al)-exposed rats. Material and methods: The whole experiment included two periods, exposure period and detoxification period, of 4 weeks each (as verified by our previous studies). 42 male Wistar rats were randomly divided into 6 groups: control group (1.0 mL/kg/day, saline, 8 weeks), Al exposure group (281.40 mg/kg/day AlCl 3 ·6H 2 O for 4 weeks during the exposure period and 1.0 mL/kg/day, saline for 4 weeks during the detoxification period), low-, medium-, and high-dose Tau groups (281.40 mg/kg/day AlCl 3 ·6H 2 O for 4 weeks during the exposure period and 200 mg/kg/day, 400 mg/kg/day, 800 mg/kg/day Tau, respectively, for 4 weeks during the detoxification period), and Tau prevention group (281.40 mg/kg/day AlCl 3 ·6H 2 O with 400 mg/kg/day Tau 4 hours after Al administration for 4 weeks during the exposure period and 400 mg/kg Tau for 4 weeks during the detoxification period). Both Al and Tau were dissolved in saline. The markers of oxidative stress, activities of antioxidant enzymes, and essential elements in the kidney were determined. Results: Al exposure caused a significant reduction in the activities of antioxidant enzymes and an elevation of malondialdehyde (MDA) in the kidney (p < 0.05). In addition, Al intake resulted in significant (p < 0.05) deficits of the essential elements copper (Cu), magnesium (Mg), and iron (Fe). However, Tau supplementation showed an improvement of the activities of antioxidant enzymes and of the levels of essential elements, evidenced by increases in glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), levels of Cu, Mg, and Fe as well as by a decrease in MDA (p < 0.05). Conclusions: Tau may be a promising intervention for Al-induced nephrotoxicity through ameliorating the impairment of oxidative stress and modulating the levels of essential elements.