Blog
About

9
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Advances in upper gastrointestinal endoscopy

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The rapidly moving technological advances in gastrointestinal endoscopy have enhanced an endoscopist’s ability to diagnose and treat lesions within the gastrointestinal tract. The improvement in image quality created by the advent of high-definition and magnification endoscopy, alongside image enhancement, produces images of superb quality and detail that empower the endoscopist to identify important lesions that have previously been undetectable. Additionally, we are now seeing technologies emerge, such as optical coherence tomography and confocal laser endomicroscopy, that allow the endoscopist to visualize individual cells on a microscopic level and provide a real time, in vivo histological assessment. Within this article we discuss these technologies, as well as some of the results from their early use in clinical studies.

          Related collections

          Most cited references 29

          • Record: found
          • Abstract: found
          • Article: not found

          High-speed optical frequency-domain imaging.

          We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We derive and show experimentally that frequency-domain ranging provides a superior signal-to-noise ratio compared with conventional time-domain ranging as used in optical coherence tomography. A high sensitivity of -110 dB was obtained with a 6 mW source at an axial resolution of 13.5 microm and an A-line rate of 15.7 kHz, representing more than an order-of-magnitude improvement compared with previous OCT and interferometric imaging methods.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Confocal laser endomicroscopy: technical advances and clinical applications.

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure

              Here, we introduce “tethered capsule endomicroscopy,” that involves swallowing an optomechanically-engineered pill that captures cross-sectional, 30 μm (lateral) × 7 μm (axial) resolution, microscopic images of the gut wall as it travels through the digestive tract. Results in human subjects show that this technique rapidly provides three-dimensional, microstructural images of the upper gastrointestinal tract in a simple and painless procedure, opening up new opportunities for screening for internal diseases.
                Bookmark

                Author and article information

                Journal
                F1000Res
                F1000Res
                F1000Research
                F1000Research
                F1000Research (London, UK )
                2046-1402
                16 December 2015
                2015
                : 4
                Affiliations
                [1 ]Department of Gastroenterology, University College London Hospital, London, UK
                Author notes

                Competing interests: The authors declare that they have no competing interests.

                10.12688/f1000research.6961.1
                4754008
                26918137
                Copyright: © 2015 Graham DG and Banks MR

                This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Product
                Funding
                The author(s) declared that no grants were involved in supporting this work.
                Categories
                Review
                Articles
                Endoscopy
                Esophagus
                Gastrointestinal Cancers
                Small Intestine
                Stomach & Duodenum

                Comments

                Comment on this article