For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
23
views
6
references
 Top references
cited by
1
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      78
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds

      other

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Polycaprolactone (PCL)-based composite scaffolds containing 50 wt% of 45S5 bioactive glass (45S5) or strontium-substituted bioactive glass (SrBG) particles were fabricated into scaffolds using melt-extrusion based additive manufacturing technique. Additionally, the PCL scaffolds were surface coated with a layer of calcium phosphate (CaP). For a comparison of the scaffold degradation, the scaffolds were then subjected to in vitro accelerated degradation by immersion in 5 M sodium hydroxide (NaOH) solution for up to 7 days. The scaffold׳s morphology was observed by means of SEM imaging and scaffold mass loss was recorded over the experimental period.

          Related collections

          Most cited references6

          • Record: found
          • Abstract: found
          • Article: not found

          Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W.

          T Kokubo, H Kushitani, S Sakka … (1990)
          High-strength bioactive glass-ceramic A-W was soaked in various acellular aqueous solutions different in ion concentrations and pH. After soaking for 7 and 30 days, surface structural changes of the glass-ceramic were investigated by means of Fourier transform infrared reflection spectroscopy, thin-film x-ray diffraction, and scanning electronmicroscopic observations, in comparison with in vivo surface structural changes. So-called Tris buffer solution, pure water buffered with trishydroxymethyl-aminomethane, which had been used by various workers as a "simulated body fluid," did not reproduce the in vivo surface structural changes, i.e., apatite formation on the surface. A solution, ion concentrations and pH of which are almost equal to those of the human blood plasma--i.e., Na+ 142.0, K+ 5.0, Mg2+ 1.5, Ca2+ 2.5, Cl- 148.8, HCO3- 4.2 and PO4(2-) 1.0 mM and buffered at pH 7.25 with the trishydroxymethyl-aminomethane--most precisely reproduced in vivo surface structure change. This shows that careful selection of simulated body fluid is required for in vitro experiments. The results also support the concept that the apatite phase on the surface of glass-ceramic A-W is formed by a chemical reaction of the glass-ceramic with the Ca2+, HPO4(2-), and OH- ions in the body fluid.
          Article 0 comments Cited 381 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Porous polymeric structures for tissue engineering prepared by a coagulation, compression moulding and salt leaching technique.

            Qingpu Hou, Dirk Grijpma, Jan Feijen (2003)
            A technique for the preparation of porous polymeric structures involving coagulation, compression moulding and particulate leaching has been developed. The technique combines the advantages of thermal processing methods and particulate leaching. A high molecular weight polymer solution in an organic solvent containing dispersed water-soluble salt particles is precipitated into an excess of non-solvent. The polymer-salt composite is then processed by thermal processing methods into devices of varying shapes and sizes, which can subsequently be extracted to give the desired porous structures. The porosities of the scaffolds could be varied between 70% and 95% by adjusting the polymer to salt ratio and the pore size could be controlled independently by varying the leachable particle size. This versatility provides for the optimisation of scaffolds used in medicine and in tissue engineering. Compared with commonly used porosifying methods such as sintering, compression moulding combined with salt leaching, and freeze-drying, this process allows excellent control over pore size and porosity and yields scaffolds with a much more homogeneous pore morphology. We have prepared porous structures from several relevant polymers in the biomedical field: poly(D,L-lactide), poly(epsilon-caprolactone) and 1000PEOT70PBT30, a segmented poly(ether ester) based on polyethylene oxide and polybutylene terephthalate.
            Article 0 comments Cited 78 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Effect of culture conditions and calcium phosphate coating on ectopic bone formation.

              Cédryck Vaquette, Cedryck Vaquette, Saso Ivanovski … (2013)
              This study investigated the effect of a calcium phosphate (CaP) coating onto a polycaprolactone melt electrospun scaffold and in vitro culture conditions on ectopic bone formation in a subcutaneous rat model. The CaP coating resulted in an increased alkaline phosphatase activity (ALP) in ovine osteoblasts regardless of the culture conditions and this was also translated into higher levels of mineralisation. A subcutaneous implantation was performed and increasing ectopic bone formation was observed over time for the CaP-coated samples previously cultured in osteogenic media whereas the corresponding non-coated samples displayed a lag phase before bone formation occurred from 4 to 8 weeks post-implantation. Histology and immunohistochemistry revealed bone fill through the scaffolds 8 weeks post-implantation for coated and non-coated specimens and that ALP, osteocalcin and collagen 1 were present at the ossification front and in the bone tissues. Vascularisation in the vicinity of the bone tissues was also observed indicating that the newly formed bone was not deprived of oxygen and nutrients. We found that in vitro osteogenic induction was essential for achieving bone formation and CaP coating accelerated the osteogenic process. We conclude that high cell density and preservation of the collagenous and mineralised extracellular matrix secreted in vitro are factors of importance for ectopic bone formation. Copyright © 2013 Elsevier Ltd. All rights reserved.
              Article 0 comments Cited 45 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Maria A. Woodruff
                Journal
                Journal ID (nlm-ta): Data Brief
                Journal ID (iso-abbrev): Data Brief
                Title: Data in Brief
                Publisher: Elsevier
                ISSN (Electronic): 2352-3409
                Publication date PMC-release: 22 January 2016
                Publication date Collection: June 2016
                Publication date (Electronic): 22 January 2016
                Volume: 7
                Pages: 923-926
                Affiliations
                [a ]Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, 4059 Brisbane, Australia
                [b ]Department of Experimental Trauma Surgery, Klinikum Rechts der Isar, Technical University Munich, Ismaninger 22, 81675 Munich, Germany
                [c ]Institute for Advanced Study, Technical University Munich, Lichtenbergstrasse 2a, 85748 Garching, Munich, Germany
                [d ]Department of Orthopaedic Surgery, Koenig-Ludwig Haus, University of Wuerzburg, Brettreichstr. 11, 97074 Wuerzburg, Germany
                [e ]Department of Materials and Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Exhibition Road, London SW7 2AZ, United Kingdom
                Author notes
                [* ]Corresponding author. mia.woodruff@ 123456qut.edu.au
                Article
                Publisher ID: S2352-3409(16)00029-9
                DOI: 10.1016/j.dib.2016.01.023
                PMC ID: 4818339
                PubMed ID: 27081669
                SO-VID: c023ec91-a5f5-43c1-9bed-1a1a3b40c816
                Copyright © © 2016 Published by Elsevier Inc.
                License:

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 13 November 2015
                Date revision received : 7 January 2016
                Date accepted : 12 January 2016
                Categories
                Subject: Data Article

                Data availability:

                Comments

                Comment on this article

                scite_

                Similar content78

                See all similar

                Cited by1

                See all cited by