+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Intra-Ocular Pressure Variations during Extracorporeal Circulation and Some Influencing Factors

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          Intra-ocular pressure (IOP) variations during extracorporeal circulation (ECC) and some influencing factors were studied prospectively in 38 patients undergoing cardiovascular surgery. IOPs were measured pre-operatively, during ECC (after 5 min, 10 min, 25 min and every 15min thereafter), and on the 1st, 2nd and 3rd postoperative days. IOP, haematocrit, arterial perfusion pressure, partial O<sub>2</sub> pressure, partial CO<sub>2</sub> pressure, pH and blood bicarbonate levels were measured simultaneously. After the beginning of ECC, arterial perfusion pressure and haematocrit values decreased suddenly, while IOP raised immediately. Sudden increase of blood volume in the beginning of ECC can be the probable cause of IOP elevation. Afterwards, IOP levels decreased to pre-ECC levels. We think that the drop is due to the effect of mannitol in the priming solution and hyposecretion of aqueous humour due to insufficient nutrition-oxygenation of corpus ciliaris after haemodynamic stabilization.

          Related collections

          Author and article information

          S. Karger AG
          31 March 2010
          : 201
          : 3
          : 140-144
          aDepartment of Ophthalmology, University of Marmara, Faculty of Medicine; bKosuyolu Heart and Research Hospital, Istanbul, Turkey
          310142 Ophthalmologica 1990;201:140–144
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 5
          Original Paper


          Comment on this article