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Cystatin C as a marker of GFR—history, indications, and future research
Guido Filler ,
Arend Bökenkamp ,
W. Hofmann ,
Thierry Le Bricon ,
Cecília Martínez-Brú ,
Anders Grubb
January 2005
January 2005
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
To summarize recent knowledge on the small molecular weight protein cystatin C (cys-C)
and its use as a marker of the glomerular filtration rate (GFR).
A multinational expert meeting was held in April 2002 in Marburg, Germany. Contributors
summarized their main findings.
Cys-C is at least equal if not superior to serum creatinine as a marker of GFR. The
independence from height, gender, age, and muscle mass is advantageous. Select patient
groups such as children, the elderly, and patients with reduced muscle mass benefit
in particular.