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      The clinical symptoms of Parkinson's disease.

      1 , 2
      Journal of neurochemistry
      Wiley-Blackwell
      Parkinson's disease, clinical symptoms, dopamine, therapy

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          Abstract

          In this review, the clinical features of Parkinson's disease, both motor and non-motor, are described in the context of the progression of the disease. Also briefly discussed are the major treatment strategies and their complications. Parkinson's disease is a slowly progressing neurodegenerative disorder, causing impaired motor function with slow movements, tremor and gait and balance disturbances. A variety of non-motor symptoms are common in Parkinson's disease. They include disturbed autonomic function with orthostatic hypotension, constipation and urinary disturbances, a variety of sleep disorders and a spectrum of neuropsychiatric symptoms. This article describes the different clinical symptoms that may occur and the clinical course of the disease. This article is part of a special issue on Parkinson disease.

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          Author and article information

          Journal
          J. Neurochem.
          Journal of neurochemistry
          Wiley-Blackwell
          1471-4159
          0022-3042
          Oct 2016
          : 139 Suppl 1
          Affiliations
          [1 ] Department of Neurology, Broomfield Hospital, Chelmsford, Essex, CM1 7ET, UK. sigurlaug.sveinbjornsdottir@meht.nhs.uk.
          [2 ] Queen Mary School of Medicine and Dentistry, University of London, London, UK. sigurlaug.sveinbjornsdottir@meht.nhs.uk.
          Article
          10.1111/jnc.13691
          27401947
          c04bbb27-5952-4789-b4ea-f5dde90c1754
          History

          Parkinson's disease,clinical symptoms,dopamine,therapy
          Parkinson's disease, clinical symptoms, dopamine, therapy

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