Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale.

Read this article at

ScienceOpenPublisherPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      The larvicidal activity of a petroleum ether extract of Zingiber officinale Roscoe (Zingiberaceae) was evaluated against Aedes aegypti L. and Culex quinquefasciatus Say (Diptera). Bioassay-guided fractionation led to the isolation of 4-gingerol (1), (6)-dehydrogingerdione (2) and (6)-dihydrogingerdione (3); the latter has not previously been reported from Z. officinale. The structures were established from infrared (IR), ultraviolet (UV), (1)H-nuclear magnetic resonance (NMR), (13)C-NMR and mass spectral data. Following a 24 h exposure, compounds 1-3 exhibited larvicidal activities against fourth instar larvae of A. aegypti (LC(50) 4.25, 9.80, 18.20 ppm) and C. quinquefasciatus (LC50 5.52, 7.66, 27.24 ppm), respectively. The results show that the most effective compound was 4-gingerol.

      Related collections

      Author and article information

      Affiliations
      [1 ] Unit of Bioactive Natural Products, Department of Zoology, C. Abdul Hakeem College, Melvisharam 632 509, India. abdulrahuman6@hotmail.com
      Journal
      Phytother Res
      Phytotherapy research : PTR
      Wiley
      1099-1573
      0951-418X
      Aug 2008
      : 22
      : 8
      18618523 10.1002/ptr.2423

      Comments

      Comment on this article