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      CrkL meditates CCL20/CCR6-induced EMT in gastric cancer.

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          Abstract

          In recent years, Crk-like adapter protein (CrkL) has been identified as a key regulator in the epithelial-to-mesenchymal transition (EMT). However, the molecular mechanisms underlying the CC chemokine receptor 6 (CCR6) and chemokine (C-C motif) ligand 20 (CCL20)-induced EMT in gastric cancer are still unclear.

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          Author and article information

          Journal
          Cytokine
          Cytokine
          Elsevier BV
          1096-0023
          1043-4666
          Dec 2015
          : 76
          : 2
          Affiliations
          [1 ] Department of General Surgery, Affiliated Hospital of Shandong Academy of Medical Sciences, Jinan, Shandong, China.
          [2 ] Department of General Surgery, Huimin County Hospital of Shandong Province, Binzhou, Shandong, China.
          [3 ] Department of General Surgery, Affiliated Hospital of Shandong Academy of Medical Sciences, Jinan, Shandong, China. Electronic address: lichengjunsdma@163.com.
          Article
          S1043-4666(15)00189-1
          10.1016/j.cyto.2015.05.009
          26044596
          c0cbbaf4-0511-4725-b859-3b6eba589b11
          History

          Erk1/2,Gastric cancer,EMT,CrkL,CCL20/CCR6
          Erk1/2, Gastric cancer, EMT, CrkL, CCL20/CCR6

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